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Lincomycin


Lincomycin is an antibacterial medication that is available under the brand name Lincocin. It is a strong antibiotic used mostly in serious infections. The strength of Lincomycin can also make very severe side effects. That is why patients who are under this medication are closely monitored by a medical professional.

Lincomycin is prescribed to those who have had serious, sometimes fatal bacterial infections. This medication is strong and it can deal with a wide spectrum of bacteria. Due to its known adverse effects, however, Lincomycin is rarely used nowadays. It is only mostly prescribed to patients who are allergic to Penicillin. Also, Lincomycin is often the resort of physicians when their patient’s bacteria developed resistance from another antibiotic they are using.

Lincomycin is available in oral and IV forms. Each ml contains 300mg of the drug. For geriatric use, the dosage requirement is between 600mg to 800mg, depending on the seriousness of the case. Naturally, the severity of infection requires a higher dosage. For pediatric use, the dosage requirement is 10mg of Lincomycin for every kg of patient. This is divided into two to three doses per day.

It is important that Lincomycin is used for the duration of the treatment period in evenly spaced intervals. That is to make sure that your body has the required amount of medication in constant level. However, caution must be seriously taken in the use and administration of the drug. For patients with renal impairment, only 25 to 30% of the dosage requirement in patients with normally functioning kidneys must be used.

If you are taking Lincomycin in oral form, you must take it with either milk or water at least one to two hours before mealtime. As it can upset your stomach, you must also not lie down for at least 30 minutes after taking the medicine.

Lincomycin is rarely used nowadays mainly due to its known side effects. It can cause an ugly case of diarrhea, stomach upset, dizziness, nausea, headache, and cramps. Unlike in other drugs where side effects disappear as the body becomes adjusted to having it around, Lincomycin can continue to cause discomforts even weeks after using it. Make sure that you keep your appointments with your doctor. Never take anti-diarrheal medicine to relieve your discomfort without first talking to your doctor. He will know if you need additional treatment to ease the symptoms of side effects.

Before taking Lincomycin, it is important that you have consulted a doctor. Tell him if you have any allergies to any drug or food. This is to ensure that you will not develop any from the components of Lincomycin. Your medical history must also be discussed, especially if you have previous intestinal infections, liver disease, or kidney ailments. Pregnant and lactating women must also discuss the possibility of transmission of the drug to their babies before taking it. Also, tell you doctor about all the medications you are currently taking (prescription and non-prescription medicines, including multivitamins). This is to avoid drug interactions that may either weaken the effects of Lincomycin or draw a different set of side effects.

Lincomycin has the following structural formula:

Chemical structure of lincomycin


• Molecular formula of lincomycin is C18H34N2O6S
• Chemical IUPAC Name is (4R)-N-[(1R,2R)-2-hydroxy-1-[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-methylsulfanyloxan-2-yl] propyl]-1-methyl-4-propylpyrrolidine-2-carboxamide
• Molecular weight is 406.5370 g/mol
Lincomycin available : 300mg tablets, 600mg tablets and 800mg tablets




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