Neostigmine is a prescribed drug for the treatment of ophthalmic condition. This cholinergic drug is also being administered after a surgery and serves as an antidote for neuromuscular blocking agents.
This drug may also be used for other medical purposes other than what is written in this article.
Neostigmine is a drug that is used to treat myasthenia gravis. It is also used to repeal the effects of muscle relaxants like tubocurarine and gallamine. This drug is being distributed under the trade name Prostigmin.
The dosage is determined by the doctor depending on the health condition, age and other factors. The success of the treatment relies on the proper dosage and period of treatment. So it is important to follow the instructions of your doctor.
Your doctor may adjust the dosage frequently to achieve the best results.
As much as possible, avoid skipping the dosage. But in case you missed a dose, you must take the medicine immediately.
Never attempt to use more than what is prescribed by the doctor to avoid overdose. Overdose may cause complications and can even be life-threatening.
Neostigmine can cause side effects. Some of the most common side effects associated by using the drug include cardiac arrest, decreased carbon monoxide, vision problem, irregular heartbeat, dizziness, convulsions, dysphonia, and drowsiness, loss of consciousness, skin rash, vomiting, diarrhea, flatulence, nausea, stomach cramps, weakness, headache, and spasms.
If any of these side effects occur, inform your doctor immediately.
Prior to medication with Neostigmine, you must inform your doctor if you have any other health problems like heart disorder, asthma, epilepsy, stomach ulcer, overactive thyroid, and problems with your circulation. Avoid using this drug if you have peritonitis or bowel obstruction.
It is also important to provide your doctor a list of all other drugs you are using including vitamins, nutritional products and herbal medicines.
If you are going to undergo dental surgery and other kind of surgery, inform your surgeon ahead of the surgery. Pregnant women and nursing mothers should also tell the doctor before using the drug. This is to prevent any risks with the baby.
Before using Neostigmine, inform your doctor if you are using drugs such as methscopolamine (Pamine), atropine (Donnatal), methantheline (Provocholine), propantheline (Pro-Banthine), clidinium (Quarzan), glycopyrrolate (Robinul), scopolamine (Transderm-Scop), and antibiotics such as neomycin (Mycafradin, Neo-Tab). Also inform your doctor if you are using heart rhythm medications like procainamide (Procan and Pronestyl), disopyramide (Norpace), dofetilide (Tikosyn), mexiletine (Mexitil), flecainide (Tambocor), propafenone (Rythmol), esmolol (Brevibloc), metoprolol (Toprol), propranolol (Inderal), quinidine (Quinidex), amiodarone (Cordarone, Pacerone), sotalol (Betapace), and tocainide (Tonocard).
If you are using any of these drugs, your doctor may not allow you to use Neostigmine or your dosage may be adjusted accordingly. This specific drug is only prescribed for certain medical conditions and should never be used to other patients without consulting a healthcare professional.
If not in use, store the medicine in a clean and safe storage. Make sure to keep it away of children’s reach to avoid any harm.
Neostigmine has the following structural formula:
• Molecular formula of neostigmine is C12H19N2O2
• Chemical IUPAC Name is [3-(dimethylcarbamoyloxy)phenyl]-trimethylazanium
• Molecular weight is 223.2915 g/mol
• Neostigmine available : 15mg tablets
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