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Acycloguanosine


Acycloguanosine, which is commonly prescribed as Zovirax, is typically used in the treatment of herpes, including genital herpes, shingles, herpes encephalitis, and herpes in people with compromised immune systems. Acycloguanosine is a member of the family of drugs known as antiviral medicaments.

Acycloguanosine is not appropriate for everyone. As such, a thorough medical history should be assessed prior to prescribing this medication. Patients with a medical history including kidney disease, liver disease, current dialysis, brain disorders, nervous system disorders, breathing problems, or electrolyte imbalances may not be able to take Acycloguanosine or may require careful monitoring while undergoing treatment with this medicine, depending on the severity of the patient's condition.

The American Food and Drug Administration rated Acycloguanosine as a pregnancy risk category B. This means that this medication is not expected to cause harm or birth defects to an unborn baby. Since herpes can be passed from a mother to child during birth, it is crucial that pregnant women are treated for herpes. Acycloguanosine does pass into the mother's breast milk and may cause harm to a nursing baby. Therefore, this medication should not be prescribed to women who are nursing.

As with all prescription medicaments, there is a risk of side effects associated with Acycloguanosine, some of which are severe. If a patient is experiencing a serious side effect or an allergic reaction they should seek immediate emergency medical assistance. An allergic reaction will present symptoms including facial skin edema, including skin edema of the lips, mouth, tongue, or throat, hives, and difficulty breathing. Other serious side effects which require emergency medical treatment include fever, chills, body aches, flu symptoms, difficulty urinating, no urine output, a red, blistering, or peeling skin rash, skin edema or pain at the injection site, skin color changes at the injection site, confusion, agitation, tremors, jaundice, pale skin, easy bruising, unusual bleeding, weakness, languidness, hallucinations, or convulsions.

Less serious side effects typically do not require emergency medical treatment but should also be reported to the prescribing physician. Patients are always encouraged to report all side effects to their doctor. Less serious side effects include headaches, lightheadedness, wamble, emesis, lack of appetite, diarrhoea, stomach pain, skin edema in the hands or feet, myalgia, numbness or tingling, insomnia or other sleep problems, and a lack of coordination. Less serious side effects can often be managed by reducing the dosage of Acycloguanosine.

Acycloguanosine should be taken exactly as prescribed by the physician. If the patient misses a dose, the dose should be taken as soon as it is remembered. However, if it is almost time for the next scheduled dose, the missed dose should be skipped to avoid the potential for an overdose. The patient should never take a double dose of this medication. If an overdose is suspected, the patient should seek immediate emergency medical attention. An overdose will present with symptoms which include decreased urination or no urination, hallucinations, agitation, and seizures.

There is a risk of drug interactions associated with Acycloguanosine. Part of your discussion with your doctor should include a thorough medical history. Patients are urged to consult with the prescribing physician before taking any new medicaments, including over the counter medicaments and herbal remedies. Medications that have known negative interactions with Acycloguanosine include probenecid and some narcotic pain relievers.

Acycloguanosine has the following structural formula:

Chemical structure of acycloguanosine


• Molecular formula of acycloguanosine is C8H11N5O3
• Chemical IUPAC Name is 2-amino-9-(2-hydroxyethoxymethyl)-3H-purin-6-one
• Molecular weight is 225.205 g/mol
Acycloguanosine available : 200mg capsules, 5% cream 2gm tube, 5% cream 5gm tube, 5% ointment 15gm tube, 200mg/5ml suspension 73ml bottle, 400mg tablets, 800mg tablets




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