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Aldecin


Aldecin, a glucocorticoid steroid medicament, is used in the treatment of a number of different conditions and has fewer side effects than other steroidal anti-inflammatory medicaments because it works directly on the lungs. As an inhaler, Aldecin is used to alleviate asthma symptoms. It is also widely used as a nasal spray to treat symptoms of rhinitis and sinusitis. Aldecin nasal spray can be used for treating nasal polyps, either to prevent their recurrence after being surgically removed or to prevent them from growing larger. This spray has also been used to treat severe cases of persistent canker sores. An ointment is also available for treating certain severe inflammatory disorders of the skin, especially in cases that do not respond to other less potent topical steroids. Aldecin has also been used to treat ulcerative colitis in conjunction with other medicaments as a controlled-release pill in the United Kingdom

This medicament is usually prescribed to those suffering from both seasonal allergic rhinitis and perennial allergic rhinitis and is used by asthma patients for the prevention of asthma attacks. Note that Aldecin is used as a preventive measure and does not stop ongoing asthma attacks. It is not typically prescribed when other existing non-steroidal medicaments already work.

The recommended dose for the inhaler varies based on the severity of the asthma symptoms and the doctor's instructions. Aldecin may be used in conjunction with other anti-asthma medicament. Continue to use the inhaler even as symptoms improve unless specifically ordered by your doctor not to.

Unless you are using a QVAR inhaler, shake the inhaler prior to each use. Exhale as much air out of your lungs as possible. Now, application can be done either by open or closed mouth inhalation. Breathe in slowly and deeply through the mouthpiece while pressing down to spray the Aldecin medicament. As you inhale, make sure the medicated mist goes down to your lungs and does not stray into your mouth or throat. Care should also be taken that the mist does not escape through the nose. After holding your breath for about 5 to 10 seconds exhale slowly. If a second shot of the inhaler is required, wait for 2 minutes before repeating the steps above.

The recommended dose for the nasal spray is about 2 sprays to each nostril twice a day, but not more than 12 applications per day for adults and 8 applications a day for children. However, always follow any specific instructions given by your doctor.

Clear your nasal passages before using the nasal spray. Put the nozzle of the nasal spray in one of your nostrils and inhale deeply as you squeeze the bottle - taking care to close the other nostril as you do this. Repeat this for the other nostril.

Aldecin may cause minor side effects such as irritation or drying of the mouth and throat, coughing, or difficulty speaking. Consult with your doctor if these become bothersome or persist.

Some side effects may require immediate medical attention. These may include rashes, difficulty breathing, swelling in the face and lower extremities, extended cold or other similar infections and muscle weakness.

Aldecin should not be used while the patient has an active infection of the mucus lining in the nose as its effects may be reduced. Report to your physician if the spit coughed up in an asthma attack becomes thicker or changes from a clear white discharge to yellow, green, or gray secretions.

Clean inhaler mouthpieces regularly in warm water and remember to re-prime nasal spray bottles by pumping twice when not used for an extended period of time.

Aldecin has the following structural formula:

Chemical structure of aldecin


• Molecular formula of aldecin is C28H37ClO7
• Chemical IUPAC Name is [9-chloro-11-hydroxy-10,13,16-trimethyl-3-oxo-17-(2-propanoyloxyacetyl)- 6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] propanoate
• Molecular weight is 521.042 g/mol




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