Beclometasone, a glucocorticoid steroid medicament used in the treatment of a number of different conditions, has fewer side effects than other steroidal anti-inflammatory medicaments because it works directly on the lungs. Beclometasone, as an inhaler, is used to alleviate asthma symptoms. As a nasal spray, it is used to treat symptoms of rhinitis and sinusitis and can be used for treating nasal polyps, either to prevent their recurrence after being surgically removed or to prevent them from growing larger. This medicament has also been used to treat severe cases of persistent canker sores. As an ointment, it is available for treating certain severe inflammatory disorders of the skin, especially in cases that do not respond to other less potent topical steroids. Beclometasone has also been used to treat colitis ulcerosa in conjunction with other medicaments as a controlled-release pill in the United Kingdom.
This medicament is given to those suffering from seasonal allergic rhinitis and perennial allergic rhinitis and is used by asthma patients for the prevention of asthma attacks. Beclometasone is used as a preventive measure but does not stop ongoing asthma attacks. This medicament is not typically given when other existing non-steroidal medicaments already work.
The usual dosage for the inhaler varies based on the severity of the asthma symptoms and your physician's instructions. Beclometasone may be used in conjunction with other anti-asthma medicament. Continue to use the inhaler even if symptoms improve unless specifically ordered by your physician not to.
For all except the QVAR inhaler, shake the inhaler prior to each use. Exhale as much air from your lungs as possible. Now, breathe in slowly and deeply through the mouthpiece while pressing down to spray the Beclometasone medicament. When you inhale, ensure that the medicated mist goes down to your lungs, not into your mouth or throat. Care should be taken so the mist does not escape through the nose. Hold your breath for about 5 to 10 seconds then exhale slowly. If a second dosage from the inhaler is needed, wait for 2 minutes before repeating the steps above.
The usual dosage for the nasal spray is 2 sprays to each nostril twice a day, but no more than 12 applications per day for adults and 8 applications a day for children. Regardless of the recommendation, follow the prescription given by your physician.
Always clear your nasal passages before using the nasal spray. Place the nozzle of the nasal spray in one of your nostrils and inhale deeply as you squeeze the bottle, taking care to close the other nostril as you do this. Repeat these steps for the other nostril.
Known side effects include irritation or drying of the mouth and throat, coughing, or difficulty speaking. Consult your physician if these symptoms become bothersome or persist.
More serious side effects include skin rashes, difficulty breathing, swelling in the face and lower extremities, extended cold or other similar infections and muscle weakness. Seek immediate medical attention if you experience any of these conditions.
Beclometasone should not be taken when the patient has an active infection of the mucus lining in the nose. This is because the effects of the medicament may be hindered. Contact your physician immediately if the spit coughed up in an asthma attack becomes thicker or changes from a clear white discharge to yellow, green, or gray secretions.
Clean inhaler mouthpieces regularly in warm water and re-prime nasal spray bottles by pumping twice when they are not used for an extended period of time.
Beclometasone has the following structural formula:
• Molecular formula of beclometasone is C28H37ClO7
• Chemical IUPAC Name is [9-chloro-11-hydroxy-10,13,16-trimethyl-3-oxo-17-(2-propanoyloxyacetyl)- 6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] propanoate
• Molecular weight is 521.042 g/mol
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