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Cefaclorum


Cefaclorum is the generic name for a second-generation broad-spectrum antibiotic from the antibacterial medicaments known as cephalosporins. It is available as the brand names Ceclor, Ceclor CD, Ceclor Pulvules, and Raniclor.

Cefaclorum is used for the treatment of bacterial infections like inflammatory illness of the lung, and infections of the ear, lung, skin, throat, and urinary tract. It works by penetrating the body's tissues and fluids, and obstructing the growth of the bacteria that is causing the infection.

Patients should not take Cefaclorum if they are allergic to cephalosporin, penicillin or other antibiotics, or if they have a kidney disorder or any digestive illness like colitis. They should inform their doctor of these illnesses and get a prescription for a different dosage and constant monitoring during the course of treatment.

In the suspension form, Cefaclorum contains sucrose, which is not advisable for diabetics. Pregnant women or those planning to become pregnant should talk with their doctor about their situation before treatment. Since Cefaclorum can be passed on through breast milk, nursing mothers need to tell their doctor if they are breastfeeding before taking any dose of the medicament, so as not to affect nursing infants.

Patients should not take antacids that contain magnesium or aluminum while under Cefaclorum treatment as these can lower the efficacy of the antibiotic. Some of these antacids are Rolaids, Maalox, Mylanta, and Milk of Magnesia. Other medicaments known to affect Cefaclorum include Warfarin (an anticoagulant), Probenecid (an arthritis and gout medicament), loop diuretics or water pills, and other antibiotics. Patients should inform their doctor of any other medicaments, vitamins or herbal supplements they are taking prior to starting their Cefaclorum treatment.

Some known side effects include allergic reactions in the form of rashes, itching, uticaria (hives), fever, serum sickness-like reactions (hypersensitivity), arthralgia (joint pain), and anaphylaxis (whole body atopy). Patients may experience diarrhea, nausea, emesis, stomach upset, transient hepatitis, jaundice, headaches and Stevens-Johnson syndrome (a deadly allergic skin illness). In rare cases, blood disorders, nephritis (kidney inflammation), hyperactivity, nervousness, disrupted sleep, hallucinations, confusion and dizziness may occur.

Patients should stop taking Cefaclorum and seek emergency medical attention if they experience severe allergic reactions which include breathing difficulties, swelling of the facial tissue, rashes, redness or itching, nausea, emesis or diarrhea, blood or mucus in their stools, or unexplained bleeding and bruising. All side effects should be reported to your doctor, particularly if they interfere with day-to-day activities.

Cefaclorum is available in purple and white 250 mg. capsules, purple and gray 500 mg. capsules, and as a suspension (liquid) in strawberry flavor. Ceclor CD is manufactured in blue tables of 375 and 500 mgs. When taking Cefaclorum in liquid form, the bottle needs to be shaken and the correct dosage accurately measured using a measuring spoon or cup.

Cefaclorum should be taken with a full glass of water on a full or empty stomach. Ceclor CD, in extended release capsules, should be taken with food or milk to prevent stomach upset. Ceclor CD pills are created to be released slowly in the body, so it is advisable not to cut, grind or chew them.

While symptoms of an infection usually disappear quickly, the bacteria causing the infection may still remain in the body. Cutting the medicament process short may cause the body to develop a resistance to the antibiotics.

Cefaclorum needs to be taken regularly for the prescribed period to make sure the body maintains a consistent level of the medicament, and to obtain the best results from it. Any unused medicament needs to be disposed of after 14 days.

Cefaclorum has the following structural formula:

Chemical structure of cefaclorum


• Molecular formula of cefaclorum is C15H14ClN3O4S
• Chemical IUPAC Name is (6R,7R)-7-[(2-amino-2-phenylacetyl)amino]-3-chloro-8-oxo- 5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• Molecular weight is 367.8074 g/mol
Cefaclorum available : 250mg capsules, 500mg capsules, 187mg/5ml suspension 100ml bottle, 375mg/5ml suspension 100ml bottle, 125mg/5ml suspension 150ml bottle, 250mg/5ml suspension 150ml bottle, 187mg/5ml suspension 50ml bottle, 375mg/5ml suspension 50ml bottle, 125mg/5ml suspension 75ml bottle, 250mg/5ml suspension 75ml bottle




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