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Alficetyn is a synthetic antibiotic that was first introduced to the medical world in 1949. Since its inception, it has been found useful as a treatment for bacterial infections caused by drug-resistant microorganisms. It has been widely used in many third-world countries because it is inexpensive when compared to other antibiotics. In the United States, however, Alficetyn is used rarely due to its suspected role in the patient's increased risk for aplastic anaemia. The only popular forms of Alficetyn in the West are ointment and eye drops, which are used to reduce the symptoms of bacterial conjunctivitis. In other countries, Alficetyn is found to be useful in treating inflammatory illness of the lung and other bacterial infections that involve the eye and the prostrate gland.

Alficetyn is administered by mouth, through an IV or topically. Oral Alficetyn comes in 250mg capsules and 125mg/5ml liquid suspension while other forms come in a variety of dosages. The usual dosage is 50mg per kilogram of body weight distributed evenly in four dosing schedules. Severe conditions require double dosage while newborns use only half since they do not metabolize the medicament as effectively.

Special precautions must be taken before the administration of Alficetyn. Young children, four years and below, who are using this treatment must be closely monitored. Alficetyn may induce abnormal activity of blood cells, which may cause serious health problems. Since it is metabolized by the liver, any form of liver disorder should be of utmost concern. People with liver and kidney diseases must receive a dosage adjustment from their doctors to avoid any more damage. Pregnant and lactating women should never take Alficetyn without the advice of their doctor. Like some other medicines, Alficetyn may pose harm to the fragile bodies of fetuses and newborns alike.

If you are using other medicaments for different conditions, inform your doctor about each one of them, including your vitamins. Some medicines react violently to Alficetyn and must not be taken together.

The reason Alficetyn did not boom in the US is its harsh side effects. The most severe of which is aplastic anaemia, a condition that is very rare yet scary because it can be fatal. It is not yet proven that blood count monitoring can prevent aplastic anaemia from occurring but it has been widely observed to reduce the possibilities of complications connected with Alficetyn treatment. The higher risk for aplastic anaemia is found in patients who are using it orally; the least risky is the eye drops form. Other possible side effects of Alficetyn include bone marrow suppression, childhood leukemia, and Gray Baby Syndrome among others.

To be safe while taking Alficetyn, make sure that you are closely monitored by a doctor. Keeping a close watch on the progress of your symptoms and on the responses of your body to the medicament will help your doctor resolve a problem early. Never take the medicine without your doctor's advice and never use another person's or an old prescription for your current condition.

Alficetyn has the following structural formula:

Chemical structure of alficetyn

• Molecular formula of alficetyn is C11H12Cl2N2O5
• Chemical IUPAC Name is 2,2-dichloro-N-[1,3-dihydroxy-1-(4-nitrophenyl)-propan-2-yl]-acetamide
• Molecular weight is 323.129 g/mol
Alficetyn available : 250mg tablets

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