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Diabaril helps control high blood sugar and prevents kidney problems, heart disease, blindness, impotency and stroke. It works by stimulating the release of insulin in the patient’s body, thereby lowering the level of blood sugar.

Diabaril is distributed under the brand names Orinase, Diabinese, and Tolinase and under several generic names including Acetohexamide, Tolbutamide and Tolazamide. This medication is for patients with type II diabetes.

Diabaril is taken orally once a day or as prescribed by your healthcare professional. The dosage will vary depending on the condition being treated and the response of the patient to the medication. Take the medicine at the same time daily for best results. Do not take more medication than prescribed to avoid overdose.

Side effects include diarrhea, weight gain, nausea, vomiting and loss of appetite. These are minor side effects but need to be reported to your healthcare professional if you experience any of these.

Serious side effects include unusual fatigue, irregular heartbeat, mood changes, weakness of the muscles, dark color stool, swelling of feet or hands, muscle weakness, vomiting, yellowish skin and eyes and stomach pains. The patient should be taken to a hospital immediately if any of these side effects occur.

Diabaril may cause hypoglycemia or low blood sugar. This is common for patients who do not consume enough calories. It is recommended that the patient always carry glucose tablets to raise the blood sugar if necessary. You may use substitutes like orange juice, candy, honey and sugar. It is essential to closely monitor your blood sugar when you are using Diabaril.

Before taking Diabaril, inform your healthcare professional if you have any allergies to this or similar medications. Also make sure your healthcare professional knows if you have other medical conditions including kidney problems, heart problems, thyroid problems, liver problem, poor diet or mineral imbalance.

The medication affects your vision and causes drowsiness so it is advised not to engage in activities that include operating machines, driving and other extreme activities.

Patients taking this medication should not consume alcoholic beverages because it increases the risk of having hypoglycemia. Alcohol negatively interacts with the medication and can cause discomfort and unwanted side effects including stomach pain, nausea, facial flushing and dizziness.

While taking Diabaril, avoid extended exposure to sunlight because the medication causes the body to be more sensitive with the sun. Patients should wear protective clothing when going outdoors.

Pregnant women and breastfeeding mothers need to consult their healthcare professional before taking the medicine to avoid risk to the baby.

This medication is prescribed by healthcare professionals and should not be shared with others.

Diabaril has the following structural formula:

Chemical structure of diabaril

• Molecular formula of diabaril is C10H13ClN2O3S
• Chemical IUPAC Name is N-(4-chlorophenyl)sulfonylmethanamide
• Molecular weight is 276.741 g/mol
Diabaril available : 100mg tablets and 250mg tablets

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