Chlorphthalidone is a thiazide diuretic, more commonly known as a water pill, used to cure fluid retention (edema) caused by the body’s absorption of salt. It transfers excess water and salt into the urine through the kidneys and is used in the treatment or control of hypertension, heart disease, kidney disorders, and side effects from taking steroids or estrogen. Popular brand names include Clorpres, Thaliton, and Hygroton.
It is essential that people unable to urinate not take this medication, as there may be severe side effects. It is also important to tell your doctor if you have asthma, kidney or liver disease, diabetes, renal dysfunction, lupus, or allergies to sulfa medications. Failure to do so may result in severe allergic reactions, sensitivity reactions, and the worst-case scenario, hepatic coma.
Studies have shown no adverse effects on unborn babies; however, breastfeeding women should tell their doctors before taking Clorthalidone.
An orally ingested medication, Chlorphthalidone is usually taken one or two times a day. If your physician prescribes otherwise, follow what they give you strictly. It should not be taken on an empty stomach, as this may result in acute discomfort. If a dosage is missed, take it as soon as you remember, but do not take more than the prescribed amount at one time. In case of overdose, immediately seek medical attention. Symptoms of an overdose include vomiting, nausea, muscle pain, and excessive weakness.
Sleep-inducing medicines, including muscle relaxants, cough medicine, and sleeping pills should be avoided while taking Chlorphthalidone, as these may exacerbate some of the side effects. If these medications must be taken, inform your doctor in advance. When taking Chlorphthalidone, make sure to avoid drinking alcohol as it can also worsen the potential side effects of the medication. Chlorphthalidone also makes skin more sensitive to UV rays, so avoid being in the sun too much or using any tanning beds. Chlorphthalidone makes the body get rid of water more quickly, so be certain to stay well hydrated.
Doctors often prescribe special diets to patients taking the medication, which are generally low in salt and sodium and high in potassium, all of which compensate for the body’s rapid water disposal.
The primary, most expected side effect of taking Chlorphthalidone is a significant increase in urination, although after a few weeks, this should also subside. Dizziness, muscle cramps, nausea, an upset stomach, vomiting, weakness, and hair loss are all potential side effects, but these are often very minimal. To be safe, immediately inform your physician if they become quite severe. In case of numbness, bruising, excessive bleeding, difficulty breathing, or fever, approach your doctor right away and have yourself checked.
Have regular blood and urine tests with your physician to make sure there are no adverse long-term effects. The medication must be stored at room temperature in a dry location. Once past the expiration date, get rid of it immediately.
Chlorphthalidone has the following structural formula:
• Molecular formula of chlorphthalidone is C14H11ClN2O4S
• Chemical IUPAC Name is 2-chloro-5-(1-hydroxy-3-oxo-1,2-dihydroisoindol-1-yl)-benzenesulfonamide
• Molecular weight is 338.767 g/mol
• Chlorphthalidone available : 25mg tablets, 50mg tablets, 100mg tablets
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