Antilepsin belongs to a group of medication called benzodiazepine, which also includes diazepam or Valium and flurazepam. Antilepsin enhances the effects of the GABA neurotransmitter, inhibiting activity in the brain.
Adults and children with various types of seizures may take Antilepsin such as akinetic, petit mal, and myoclonus seizure. It is also effective for relieving short-term anxiety symptoms. This medication can be used to complement other medications for seizure disorders.
Dosage of Antilepsin depends on the patient. Adults suffering from seizures take 1.5 milligrams three times a day. The dosage can be increased up to 1 milligram daily until the seizures are controlled. For patients with panic disorders the initial dose is .25 milligrams twice a day. The dose can be increased up to 1 milligram a day after 3 days.
The most common side effect associated with Antilepsin is sedation. Almost half the patients who use Antilepsin have experienced sedation, while 1/3 of the patients experience dizziness, unsteadiness, and weakness. Other side effects may include headache, difficulty in sleeping, loss of orientation and depression.
The use of Antilepsin can also result in physical dependence typical with all benzodiazepines. Those who suddenly stopped using the medication may feel side effects such as insomnia and agitation. Those who use Antilepsin for a longer period than prescribed by a physician may experience muscle cramping, seizure, vomiting, tremors, and sweating.
Like most antiepileptic medications, the use of Antilepsin results in an increased risk of users having a suicidal behavior. Those who use Antilepsin should balance such risk with the clinical requirement for antiepileptic medication.
Antilepsin also heightens the effects of medications that slow down the brain processes such as alcohol, narcotics, and barbiturates.
Pregnant women are discouraged from using Antilepsin since it has been linked to fetal damage especially in the first few months of the pregnancy. Most doctors discourage women from taking Antilepsin throughout pregnancy.
Before taking Antilepsin, users should inform their doctors if they have any allergy especially to benzodiazepines such as lorazepam and diazepam. Patients who have had liver disease, glaucoma, medication dependency, kidney disease, breathing disorder, and mental disorder should divulge their conditions before agreeing to take this medication.
The use of Antilepsin may make a patient dizzy or drowsy, so one should be cautious when driving or operating machinery. The elderly are also more susceptible to the side effects of Antilepsin such as confusion and drowsiness.
Antilepsin can have serious interaction with sodium oxybate. If a patient is presently using the medication, he or she must immediately inform their physician before beginning to take Antilepsin. Patients should also tell their doctors of the medications - whether prescription or non-prescription - that they are taking.
Anti-depressants such as fluoxetine, nefazodone, fluvoxamine can also have interactions with Antilepsin. Likewise other medications that result in drowsiness such as antihistamines, anti-anxiety, and anti-seizure medications may interact negatively with Antilepsin.
Antilepsin has the following structural formula:
• Molecular formula of antilepsin is C15H10ClN3O3
• Chemical IUPAC Name is 6-(2-chlorophenyl)-9-nitro-2,5-diazabicyclo[5.4.0]undeca-5,8,10,12-tetraen-3-one
• Molecular weight is 315.711 g/mol
• Antilepsin available : 0.5mg tablets, 1mg tablets, 2mg tablets
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