Lepotex has proven useful in the treatment of schizophrenia although it tends to cause serious side effects if used improperly. It is best to know the third-line treatment regimen to improve mood the right and safe way.
Lepotex is the generic name of the antipsychotic medication that blocks several receptors for neurotransmitters. It is primarily used to treat schizophrenia symptoms in patients who have not gotten results from other medications. Lepotex belongs to a medication class called atypical antipsychotics, which alter the activity of substances and chemicals in the brain. The medication is available under the brand names Clozaril, Gen-Clozapin and Fazaclo.
The medication comes in tablet form and is taken orally. It has a number of side effects that are considered lethal, which explains why it was categorized under third line treatment. Lepotex has been more helpful in treating schizophrenia symptoms compared to older antipsychotic medications. Other uses for this medication include treating suicidal patients, paranoid individuals, manic patients, insomniacs and those suffering from schizoid personality, and dementia of the Lewy-body-type.
LEPOTEX SIDE EFFECTS
Drowsiness is the most common side effect. Some patients may experience increased heart rate, headache, weight gain, sleepiness, tremor, increased salivation, hypotension, fever, blurred vision, difficulty urinating, constipation and paralytic ileus. Some side effects may disappear after taking the medication for 2 to 3 days. In rare cases, the medication may cause extrapyramidal effects or sudden involuntary movements of the extremities, eyes and head. A serious side effect is agranulocytosis where white blood cell count drastically drops making the patient vulnerable to infection and other diseases. Other rare side effects include seizures, myocarditis, jaundice, cardiomyopathy, pulmonary embolism, respiratory depression and chest pain. If you experience any of these, they should be reported to your physician right away.
LEPOTEX DURING PREGNANCY
Pregnant women and breastfeeding mothers should talk with their physician before taking Lepotex. The medication may interact negatively with other medications including risperidone, cimetidine, epinephrine, quinidine, anti-seizure medications, phenytoin, sedatives, SSRIs or selective serotonin reuptake inhibitors and tranquilizers. Physicians should be fully informed about any herbal medicine or nutritional supplement that the patient is taking to avoid adverse reactions. Patients with known allergic reactions to the medication should not take it. Patients with a history of liver disease, kidney problem, lung problem, hypotension, leukemia, hypertension, glaucoma, diabetes and mental illness should take the medication cautiously.
Lepotex acts by binding to serotonergic and dopamine receptors particularly dopamine at D1, D2, D3 and D5 receptors. It is also a 5-HT1A receptor partial agonist, which improves mood. Furthermore, it acts as an antagonist at various adrenergic, histaminergic and cholinergic receptors. Once Lepotex is metabolized in the liver, it binds to brain receptors improving dopamine and serotonin levels, which are responsible for mood. As a result patients exhibit improvement from schizophrenic symptoms.
In a study, 24 schizophrenic patients were given Lepotex for a span of 16 weeks. The initial dosage was 25 mg a day during the first week and amounts were increased every two weeks until patients took around 400 mg during the last 2 weeks. During the first 4 weeks, 14 patients showed significant improvement in symptoms. Another 6 patients improved during the next 4 weeks until 21 out of 24 were stable at the end of the study. These patients were provided with Lepotex after 2 other medications were rendered ineffective.
Lepotex is a prescription medication and should only be purchased at legitimate pharmacies and clinics. There are sources that sell over the internet but consumers should make sure that these are authentic and certified. Consumers may ask for certification when buying online.
Avoid alcohol and tobacco products while taking Lepotex as these may decrease the effectiveness or exacerbate drowsiness. Long-term use should be monitored since tardive dyskinesia and agranulocytosis may result. Patients should expect results within the first 4 to 6 weeks but continuous improvement is possible over 6 months to 1 year.
Lepotex has the following structural formula:
Molecular formula of lepotex is C18H19ClN4
Lepotex available : 25mg tablets, 100mg tablets
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