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Amphepramon, also known as Diethylcathinone, is a type of sympathomimetic stimulant medicament that is marketed as an appetite suppressant. It is known in the market by the name Tenuate or Tenuate Dospan and is very similar to amphetamine. Amphepramon is an anorectic or anorexigenic medicament.

This medicament is a chemical analog to a similar antidepressant found to be effective as medicament to stop smoking. Amphepramon stimulates the central nervous system, which may increase the heart rate and blood pressure and decrease a patient’s appetite.

Marketed as an appetite suppressant, this controlled substance is used to treat obesity, used for diet, and may even sometimes be used to counter depression. Amphepramon has been listed by the FDA in pregnancy category B meaning it is found to not cause any harm to an unborn baby. Expecting mothers should not take this medicament without consulting their doctors.

Amphepramon is a controlled substance Schedule IV, meaning it can be obtained only with a prescription. The medicament comes in 25 mg pills and 75mg control-released pills by the names Tenuate, Ten-Tab and Teparil.

Amphepramon affects the central nervous system, having side effects such as nausea, cephalalgias, bouts of insomnia, psychosis, and the more serious side effects such as pulmonary high blood pressure, and ultimately a stroke.

Less common side effects include xerostalmia, or a metallic taste in foods, blurred vision or photosensitivity, and allergies and rashes. Greater and more serious side effects include decrease in the patient’s libido (sexual activity), which may lead to eventual erectile dysfunction. There have been reported neurological and psychological side effects brought about by Amphepramon such as depression, anxiety, drilling cephalalgias, restlessness, tremors, dizziness and seizures.

Caution is always emphasized when taking Amphepramon, especially if performing activities such as driving or machine operation. Amphepramon is a stimulant medicament, masking tiredness, which causes fatigue leading to problems in vision, speech and motion. Amphepramon is habit forming.

Patients with a recorded history of heart diseases or high blood pressure are not advised to take Amphepramon. This also includes patients diagnosed with the condition arteriosclerosis or the stiffening of the arteries. Patients suffering from glaucoma are not to take this medicament.

Patients taking monoamine oxidase inhibitor medicaments (Monoamine oxidaseIs) within the last two weeks may not be able to take Amphepramon, as mixing Monoamine oxidaseIs with Amphepramon may have a lethal effect on the patient. Patients with a known history of medicament and alcohol abuse are prohibited from taking the medicament as it is habit forming and they may have a hard time stopping the use of the medicament.

Amphepramon may not be taken with other anorectic medicaments that may be prescribed, over the counter or herbal medicaments. Pregnant women should only use this medicament if clearly needed. Breastfeeding women should weigh the benefits of taking the medicament against the potential risk it may bring to the nursing infant prior to taking the medicament.

Amphepramon has the following structural formula:

Chemical structure of Amphepramon

• Molecular formula of Amphepramon is C13H19NO
• Chemical IUPAC Name is 2-diethylamino-1-phenylpropan-1-one
• Molecular weight is 205.2961 g/mol
Amphepramon available : 25mg tablets and 75mg tablets

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