Salbutamol is a Beta2-adrenergic receptor agonist drug that is used for the relief of asthma and chronic obstructive pulmonary disease. It was first introduced in the United Kingdom in 1969 and in the United States in 1980. It is also known by the trade name Ventolin.
Like other Beta2-adrenergic receptor drugs, Salbutamol works by relaxing the muscles in the lungs and opening the air passageways to relieve breathing difficulty. It is usually taken in inhaler form where the mist is orally taken by the mouth for a more direct effect. Salbutamol is also available in liquid formula which is either taken orally or through an IV but patients and doctors alike prefers the inhaled solution because it offers maximal effect. After a dose, asthmatic patients may feel relief within five to twenty minutes.
The usual dosage of Salbutamol for children depends on their age and body weight. 2 to 6-year-olds must not exceed the 4mg dosage mark of Salbutamol, divided into three dosing times a day. The maximum dosage for 6 to 12-year-olds is 24mg a day. This is administered three to four times daily. For children over 12 years and adults, the daily dosage must not exceed 32mg. This is divided into three or four doses.
The use of inhaler or nebulizer must be administered properly. If you do not know how to use both, you must take a lesson from your doctor. If your children are the ones in need of it, you must keep a close watch on them while they are inhaling Salbutamol to ensure that they are doing it the right way.
Salbutamol is hypersensitive to some other drug ingredients. As such, it could cause adverse reactions when used alongside other drugs, especially when you are taking it orally or intravenously in high doses. The common adverse effects include headache, tremor, and palpitations. More severe effects include muscle cramps, agitation, hypokalemia, insomnia, and hyperactivity in children.
Care should be taken when using Salbutamol to patients with heart disease and diabetes. It must also be avoided by pregnant women altogether. The use of Salbutamol by pregnant women who are in their third trimester may affect the contractions of the uterus during labor.
Never attempt to share your Salbutamol prescription with someone else, even if he is experiencing the same symptoms as yours. Patients react to drugs differently. Your level of affliction may be different to that of the other. Also, remember that your medical history is involved in the proper administration of the drug. This means that, there is a very slight chance that your dosage requirement is similar to that of another person. Do not use an old prescription for a current condition as well. Dosages vary every single time that the symptoms become evident. Always consult your doctor before taking Salbutamol to ensure that you are using the right amount for the right reasons. Only your doctor would determine, after making you go through series of tests, how much Salbutamol you need in your system.
Salbutamol has the following structural formula:
• Molecular formula of salbutamol is C13H21NO3
• Chemical IUPAC Name is 2-(hydroxymethyl)-4-(1-hydroxy-2-tert-butylamino-ethyl)-phenol
• Molecular weight is 239.311 g/mol
• Salbutamol available : 200mcg capsules, 2mg tablets, 4mg tablets
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