Categorized under a class termed as sulfonylureas, Glamide is a drug designed to regulate the amount of sugar in the blood. More specifically, it is prescribed for type 2 diabetes, which is a form of diabetes that results from the body’s inability to produce enough insulin. Sometimes, type2 diabetes occurs when the body does not respond to insulin properly. Insulin is the hormone that aids your body control the amount of sugar present in the blood.
Marketed under the name Glyburide, Glamide comes in tablet form and is taken once a day. The patient is usually prescribed with a dosage ranging from 2.5 – 5 milligrams which he must take with his breakfast. However, depending on the severity of the type 2 diabetes, the doctor may choose to ask the patient to take the doses twice a day.
Before starting Glamide, the patient should get some tests done to see whther he may have an allergic reaction to Glamide and its ingredients.
More than knowing your allergies, it is also important to tell your doctor about any other medication that you are taking.
Since Glamide’s functions are very interconnected with the blood and circumstances around it, it would be beneficial to tell the doctor if you are taking any anti-coagulants (blood thinners). Usual anti-coagulants are warfarin (Coumadin) and dexamethasone (Decadron). Knowing your blood medication will help make sure that Glamide does not interfere or oppose the actions of the anti-coagulant.
Also, if you are undergoing hormone therapy and are taking estrogen, you must also inform your doctor. Glamide will increase insulin and since both insulin and estrogen are hormones, the doctor must make sure that there will be no adverse effects due to the simulatanous increase of both hormones.
Taking oral contraceptives and certain form of vitamins and supplements may also interact negatively wtih Glamide so consult your doctor to see if it is compatible with your current set of medication.
If you are taking medication for heart disease or if you have a personal history of heart disease, tell your doctor too.
Also, if you have any impending medical surgery, do infrom your surgeons that you are takign Glamide as it may affect the way your body will respond to the procedure. Even minor surgeries like tooth extractions must be reported to your doctor.
There are some instances where Glamide can make you sleepy. Once you feel this effect, avoid driving or operating delicate mahinery.
In regulating your blood sugar, Glamide may give effects similar to having either hypoglycemia or hyperglycemia.
In hypoglycemia where your blood sugar is too low, you may experience fatigue, hunger, sweating and you may also observe jerkiness in your movements. You may also feel dizzy and irritable. If your blood sugar decreases significantly, you may feel dazed and confused. You may even get seizures or lose consciousness. Once you feel mild symptoms of hypoglycemia, drink some fruit jiuce or eat some hard candy and contact your doctor.
On the other hand, the changes in blood sugar levels may make you experience hyperglycemia, a condition where there is excess sugar in the blood. In this condition, you may feel extreme thirst and hunger. You will urinate much more frequently and your vision may be blurred. Overall, you will feel weak and tired.
However, do not worry since hypoglycemia and hyperglycemia are extreme cases. Usually, side effects of Glamide are simple cases of skin rashes or skin itching and redness. You may also notice yellowing in your complexion. You may get unusual bruising in your body. You may also notice that your urine is lighter while your stool is much darker.
Glamide has the following structural formula:
• Molecular formula of glamide is C23H28ClN3O5S
• Chemical IUPAC Name is 5-chloro-N-[2-[4-(cyclohexylcarbamoylsulfamoyl)phenyl]ethyl]-2-methoxy-benzamide
• Molecular weight is 494.004 g/mol
• Glamide available : 1.25mg tablets, 2.5mg tablets, 5mg tablets
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