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Terazosin


Terazosin, also known as Hytrin, belongs to a group of medicines called alpha-adrenergic blockers. It is used to relax and expand blood vessels in order to improve a patient's blood flow. It is also utilized for muscle relaxation in the bladder neck and prostrate, which makes it easier for a person to urinate. As such, Terazosin is mostly used for high blood pressure and enlarged prostrate treatment.

One milligram before sleeping is the initial recommended dose for most everyone. Therefore, this dose should never be altered as a starting dose. Terazosin takers should be closely monitored during starting administration to decrease the risk of a critical hypotensive reaction.

As for subsequent doses, each dose should be increased in an incremental way. That is, start with two milligrams, then five, then ten once daily to get the desired effect and to alleviate symptoms and/or flow rates. For clinical response, doses of ten milligrams daily are generally needed. You need to take this dose for four to six weeks to see whether the treatment is effective or not.

If you have any other blood pressure medications like verapamil, you need to inform your doctor about it before taking terazosin. It's because you may need to adjust your dosage if you take terazosin with other similar drugs and medicines. Moreover, watch out for light-headedness or dizziness after your first few doses or if you stopped taking it for any reason and then started taking it again.

This drug is FDA pregnancy category C, which means that it may be hazardous to the unborn baby. Consult your doctor before taking this medicine if you are pregnant or plan to get pregnant during treatment.

Additionally, there have been no conclusive findings whether terazosin passes into breast milk or not. Although most drugs pass into breast milk in miniscule amounts, many of them can be used safely even if a patient breastfeeds. Ergo, mothers taking terazosin should further discuss this situation with their healthcare specialist.

Furthermore, because terazosin lowers blood pressure, there's a chance that you might faint when taking this medicine. In order to not be inconvenienced by this possible side effect, take terazosin before you sleep. Consider taking this medication only at bedtime if it makes you feel dizzy or faint.

Be warned that this medication can also affect your pupils during cataract surgery. Before having cataract surgery, tell the surgeon ahead of time that you are currently having a terazosin treatment. Do not stop the treatment before surgery unless your surgeon explicitly tells you to do so.

Taking in terazosin may cause loss of appetite, drowsiness, nasal congestion or dry eyes, constipation, headache, dizziness, or fatigue. These are this drug's most common side effects, and they mostly go away after a few days of use. To avoid the first dose phenomenon of dropping blood pressure, treatment should be started with a low dose. Priapism, erectile dysfunction, and other sexual effects are rare side effects, but they do happen.

The foremost side effect of terazosin is dizziness or fainting, especially during your first few doses or when you begin taking it again. Dizziness usually happens when you first wake up after initial treatment, so be careful when sitting or standing up from a prone position while under treatment.

Terazosin has the following structural formula:

Chemical structure of terazosin


• Molecular formula of terazosin is C19H25N5O4
• Chemical IUPAC Name is [4-(4-amino-6,7-dimethoxy-quinazolin-2-yl)piperazin-1-yl]-tetrahydrofuran-2-yl-methanone
• Molecular weight is 387.433 g/mol
Terazosin available : 1mg capsules, 2mg capsules, 5mg capsules, 10mg capsules




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