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Actonel is an osteoporosis pill that is said to treat the condition as well as prevent it. It belongs to the class of drugs known as bisophonates. It works by modifying bone formation and its breakdown in the body preventing fractures in the process. Actonel acts doubly; it slows down bone loss and increases bone mass.

Aside from osteoporosis, Actonel is also used to treat Paget’s Disease.

Actonel comes in tablet form of different strengths. Your dosage and dosing schedule depends on your doctor’s assessment regarding your need for as well as your risks with the drug. Some tablets are prescribed for use once a day, others are used once a week. Stronger tablets are prescribed to be used once or twice a month. If you change your tablet strength, make sure that your dosing schedule is also altered.

Actonel is advised to be taken in the morning, before your morning meal or anything else for that matter. After your drug intake, you must wait 30 minutes before you take in anything, food or beverage other than water, and your other medications as well. You must also refrain from reclining or lying down for half an hour after you take your medicine.

Actonel is mostly prescribed in conjunction with a specially designed program. It is important that you follow all your doctor’s instructions regarding your food intake and physical activities while under this treatment to ensure not just the efficiency of the medicine but your safety with it as well.

The use of Actonel requires extra precautions. Before you take this medicine, make sure that you have talked to your doctor about your medical history, your current drug intakes, and the specific condition that you are treating with Actonel. Low blood calcium, liver dysfunction, vitamin D deficiency, stomach ulcers, cancer, and blood disorders must be taken to your doctor’s attention. Such conditions may require you to be given a dosage adjustment or a different drug altogether.

Actonel may cause high risk for osteonocrosis in the jaw. This is mostly seen in cancer patients given bisophonates. The interaction of Actonel with chemotherapy and radiation therapy drugs are said to cause the problem. Osteonocrosis was also associated with existing dental problems and even minor or major dental surgery.

As a safety measure, your doctor may request for bone density and liver function tests while you are under Actonel treatment. This will help him to monitor your progress with the drug as well as your symptoms of side effects.

Actonel causes side effects; some are mild and some are severe. Side effects are symptoms that occur in conjunction with the use of the drug. Most likely, the side effects go away as soon as your body becomes adjusted to Actonel. If your diarrhea, heartburn, joint pains, and headache do not go away or become worse, talk to your doctor. You must also tell your doctor if you experience any of the less common but serious side effects such as chest pain, difficulty swallowing, and jaw pains.

Actonel has the following structural formula:

Chemical structure of actonel

• Molecular formula of actonel is C7H11NO7P2
• Chemical IUPAC Name is (1-hydroxy-1-phosphono-2-pyridin-3-yl-ethyl)phosphonic acid
• Molecular weight is 283.112 g/mol
Actonel available : 5mg tablets, 30mg tablets, 35mg tablets, 75mg tablets and 150mg tablets

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