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Betaxolol is a selective beta blocker which is both used for the treatment of hypertension and glaucoma. This beta blocker produces far less complications than other beta blockers and can reduce eye pressure, presumably by reducing production of the aqueous humor inside the eye. This reduces the risk of damage to the optic nerve and loss of vision resulting from glaucoma.

Like other beta blockers, it works on reducing blood pressure by affecting the action of the sympathetic nervous system, which is in part responsible for blood pressure regulation.

Betaxolol comes in 10 mg oral tablets for the treatment of hypertension (available in brand names such as Kerlone) and in ophthalmic solutions in 0.25% and 0.5% concentrations (brand available as Betoptic).

Betaxolol can be administered alone or along with other medicines (like hydrochlorothiazide) in some cases to treat high blood pressure as a part of a larger hypertension treatment program. The eyedrops are used to prevent permanent vision loss arising from increased internal pressure in the eyes for those suffering from glaucoma.

Regardless whether you are using betaxolol to treat hypertension or glaucoma, always follow specific instructions given by the doctor.

Shake the bottle well before each dose if you are using betaxolol in a suspension eye drop form (Betoptic S). If using the eye drop solution form, shaking will be unnecessary. Squeeze in the prescribed amount of drops into the “pocket” made by the pulling down lower eyelid gently. Droping the eye medication directly onto the eyeball may cause a stinging sensation. Close the eye and lightly press lower eyelid against your eyes with your finger for 2 to 3 minutes. Do not blink as the medication may spill out.

Betaxolol manages glaucoma by controlling the increase of pressure but does not cure it so continuous use is advised even when symptoms start to disappear. Do not discontinue your betaxolol treatment without consulting your doctor.

For the control of hypertension, a 10 mg dose once a day either alone or with other medication is advised. The optimal effect of the medication can normally be oberseved in one to two weeks. The dose may be doubled by your doctor after another one to two weeks if improvements are not observed. However increasing the dose beyond 20 mg has not yet seen an observable benefit but studies have observed doses up to 40 mg to be tolerable by the body. An increased effect on the heart rate should be observed but if no improvements can be seen an accompanying diuretic treatment may be advised.

Side effects experienced when using the eye drops may include eye irritation and tearing, headaches, insomnia and dizziness. If these effects persist, consult with your doctor. More serious effects requiring immediate medical attention includes difficulty in breathing, eyesight problems and pain in the eyes.

Oral betaxolol medication use may cause decreased sex drive or even impotence, insomnia, tiredness or anxiety and nervousness. However, inform your doctor and seek medical attention if you experience symptoms of allergic reaction, irregular heartbeats, depression, swelling in the lower extremities, dark urine and clay-colored stools and nausea.

Using betaxolol eye drops along with other oral beta blockers may combine for an increased effect and may result in an excessively low blood pressure. Do not immediately withdraw oral betaxolol treatments as withdrawal symptoms may cause irregular heartbeat and aggravation of certain heart conditions.

Betaxolol has the following structural formula:

Chemical structure of betaxolol

• Molecular formula of betaxolol is C18H29NO3
• Chemical IUPAC Name is 1-[4-[2-(cyclopropylmethoxy)ethyl]phenoxy]-3-(1-methylethylamino)propan-2-ol
• Molecular weight is 307.428 g/mol
Betaxolol available : 10mg tablets and 20mg tablets

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