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Clobetasol


Clobetasol is a drug used for the treatment of various skin disorders such as eczema. It is available in ointment as well as emollient cream.

Clobetasol, which has a generic name of clobetasol propionate, is recommended for use among adults and children below 12 years of age. Clobetasol is anti-inflammatory and antipruritic. It is recommended to those suffering from various skin disorders like eczema, rashes, allergies, and dermatitis. It reduces the swelling, redness, and itching that typify these skin disorders.

Clobetasol is usually applied on the skin twice a day. However a physician can increase the dosage according to the severity of the disorder. The drug should be used only on the skin. It should never be applied on the face, underarms, or groin unless instructed by a physician.

Users should make first wash and dry their hands before using Clobetasol. The affected area should be cleaned and dried. The area should not be covered or bandage unless instructed by a physician.

After applying Clobetasol, users should immediately wash their hands. In case the drug is accidentally applied on the eyes, mouth, or nose, immediately rinse the area with lots of water.

Clobetasol should not be used for more than 2 weeks. The dosage should also be kept under 50 grams a week.

In case the conditions continue, patients should immediately consult their physicians.

Clobetasol can result to some side effects, so patients should inform their doctors in the event that they notice these. Some of the side effects that may result from use of Clobetasol include a burning, itching, or stinging sensation at the area being treated. Usually these conditions should improve after a few days once the body becomes used to the medication. However when the conditions persist, patients should talk to a doctor as soon as possible.

However, most of the time users of Clobetasol do not experience these side effects, so the chances of a person experiencing those conditions are quite low.

Some of the more serious side effects include discoloration of the skin, acne, stretch marks, unwanted growing of hair, and folliculitis or hair growth.

It is also very rare that a person develops allergy to this drug. However patients are advised to get immediate medical help in case they notice symptoms of allergic reaction such as rashes, swelling, itching, severe dizziness, and difficulties in breathing.

Before agreeing to use Clobetasol, patients should tell their doctors any history of allergy to corticosteroids like prednisone or if they are allergic to any medication. Patients should also inform their physicians of their medical history particularly if they have problems in blood circulation and immune system, as well as skin disorders like rosacea.

Clobestasol should not be used on a sore or infected area.

There is also a possibility—albeit very low—that Clobestasol can enter the bloodstream. It can lead to undesirable results requiring corticosteroid treatment. This may happen to children or those who used the medication for an extended period of time. Some of the symptoms that may arise as a result include vision problems, unexplained weight loss, and persistent headache.

Clobetasol has the following structural formula:

Chemical structure of clobetasol


• Molecular formula of clobetasol is C25H32ClFO5
• Chemical IUPAC Name is [17-(2-chloroacetyl)-9-fluoro-11-hydroxy-10,13,16-trimethyl-3-oxo- 6,7,8,11,12,14,15,16-octahydrocyclopenta[a] phenanthren-17-yl] propanoate
• Molecular weight is 466.97 g/mol
Clobetasol available : 0.05% cream 15gm tube, 0.05% cream 30gm tube, 0.05% cream 45gm tube, 0.05% cream 60gm tube, 0.05% gel 15gm tube, 0.05% gel 30gm tube, 0.05% gel 60gm tube, 0.05% ointment 15gm tube, 0.05% ointment 30gm tube, 0.05% ointment 45gm tube, 0.05% ointment 60gm tube, 0.05% solution 50ml bottle




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