Aceon is a member of the family of medications known as ACE inhibitors, and can be generically prescribed as perindopril. ACE inhibitors are used to treat patients with coronary artery disease to prevent heart attacks as well as used to treat hypertension.
Patients who are pregnant should never take Aceon or any other angiotensin converting enzyme inhibitors. The American Food and Drug Administration rated Aceon as a pregnancy risk category D, which means that there is a high likelihood that this medication will cause harm or birth defects in a developing fetus. Aceon passes through breast milk content and can affect a nursing infant. Aceon is not appropriate for women who are nursing.
Not all patients will be able to tolerate Aceon and a thorough medical assessment is necessary in order to determine the patient’s ability to handle Aceon. Patients who have a medical history which includes liver disease, kidney disease, additional heart complications, dialysis, congestive heart failure, lupus, scleroderma, rheumatoid arthritis, or other connective tissues disorder are likely to require careful monitoring while undergoing drug therapy with Aceon, or may not be able to take it at all. The condition, the overall health of the patients, and the severity of the condition are likely to determine the patient’s ability to take Aceon.
A few patients may experience significant side effects which will require urgent medical assistance. Allergic reactions, facial swelling, swelling of the lips, mouth, tongue, or throat, difficulty breathing, and hives, require immediate medical assistance. Symptoms including chest pain, uneven heart rate, pounding heart, jaundice, swelling or rapid weight gain due to edema, fever, body aches, chills, flu symptoms, lightheadedness, fainting, pale skin, the ability to bleed or bruise easily, excessive fatigue, muscle weakness, changes in frequency of urination, or no urine output at all are all symptoms of serious side effects which require emergency medical treatment.
Patients are more likely to experience side effects that do not require emergency medical treatment, although patients should always refer to side effects when reporting their condition to the physician. Side effects such as stuffy nose, cough, mild congestion, headaches, dizziness, drowsiness, diarrhea, stomach upset, muscle pain, joint pain, insomnia or other sleep problems, mild itching, skin rash, or a generally bothersome feeling of fatigue are quite common and might be alleviated to a tolerable degree with a dosage adjustment.
Patients should not adjust their own dosing while taking Aceon, it should be taken exactly as it has been prescribed by the physician. Taking too much Aceon may result in an overdose if the patient double doses or takes doses too closely together. An overdose may present with symptoms which include extreme dizziness, lightheadedness, fainting, and heart rhythm changes.
Aceon presents a risk of drug interactions if taken with certain other medications. Patients should be warned never to take any additions medicines, over the counter or prescriptions, or vitamin or herbal supplements without the prescribing physician’s permission. Drug interactions can be as mild as making a medication less effective and can be as serious as death. Aceon is likely to interact with medications including potassium supplements, diuretics including bumetanide, chlorthalidone, ethacrynic acid, furosemide, hydrochlorothiazide, indapamide, metolazone, spironolactone, triamterene, or torsemide, lithium, or salt substitutes.
Aceon has the following structural formula:
• Molecular formula of aceon is C19H32N2O5
• Chemical IUPAC Name is 1-[2-(1-ethoxycarbonylbutylamino)propanoyl]-2,3,3a,4,5, 6,7,7a-octahydroindole-2-carboxylicacid
• Molecular weight is 368.468 g/mol
• Aceon available : 2mg tablets, 4mg tablets, 8mg tablets
Generic name: Perindopril
Brand name(s): Coversyl, Coversyl Plus, Preterax
Review published on: 09 June 2007
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