Adalimumab review

Adalimumab is a drug used for treating diseases like rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, chronic psoriasis, juvenile idiopathic arthritis and Crohn s disease.

Adalimumab works in reducing the pain and swelling associated with rheumatoid arthritis. What it does is that it prevents the tumor necrosis factor that is found in the immune system that is causing the swelling and avoids further damage to the joints of the patient.

Adalimumab is the generic name of a drug manufactured and distributed by Abbott Laboratories under the brand name Humira. Humira is an abbreviation that stands for Human Monoclonal Antibody in Rheumatoid Arthritis.

Adalimumab is a drug proven to be very effective in treating different arthritis conditions. It shows positive results in reducing the symptoms to patients with rheumatoid arthritis.

Compared to other conventional treatment, Adalimumab is best proven to reduce the risks involved caused by Crohn’s disease in adults.

Adalimumab comes in a 0.8ml syringes and are injected to the patient when administered. The drug is administered in that method so as to prevent the medicine from being destroyed by the digestive system.

A 40mg of the drug given every other week is the recommended dosage for most adult patients. However, there are some patients that may require a weekly dosage that can be determined by the doctor.

The most common side effects of caused by using Adalimumab includes rashes, headache, stomach pains and nausea. The area of the skin where it was injected may experience itching, swelling, pain and redness.

Since Adalimumab suppresses the immune system, it sometimes causes sinuses, tuberculosis and urinary tract infection. This also affects the normal function of the immune system to protect the body against any infection. More serious side effects may also occur to patients such as irregular heartbeat, mood changes, seizure, chest pains, yellow skin or eyes and swelling of the legs.

If any of the side effects occur, your doctor should be notified immediately to avoid risks of more serious health problem.

Since this drug can be very fatal when administered incorrectly, it is highly recommended to consult a doctor. It is also advised that prior to medication, the patient should undergo a TB or tuberculosis test. If diagnosed with TB, the patient should avoid medication and must be treated first for the tuberculosis to avoid other infections.

Also avoid using the drug if you have an existing medical problem. Inform your doctor about your condition especially if you have any history of cancer, brain disorder and any other health problem such as allergies.

Chemical reactions may occur when using Adalimumab with other drugs that may affect its effectiveness and may even cause serious health problems. Avoid using Anakinra, live vaccines, TNF blockers together with Adalimumab because it can cause serious infections. Methotrexate is also known to absorb the amount of Adalimumab by about 49%. It would be best to inform your doctor of any other medicines you are taking prior to using Adalimumab.

Before injecting, make sure that your syringes are well sterilized. Follow all the instructions on the package or as advised by your doctor.

• Molecular formula of adalimumab is C6428H9912N1694O1987S46
• Chemical IUPAC Name is Humanized anti-TNF antibody (D2E7)
• Molecular weight is 144190.3 g/mol
Adalimumab available : 20mg tablets and 40mg tablets

Brand name(s): Humira

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