Adamantamine review

Adamantamine, also known as Symmetrel, is a manmade anti-viral medication that can hamper the duplication of viruses within cells. Currently, how it works in treating Parkinsons disease is unknown. The effects it has on the illness may be connected to its ability to increase or amplify the effects of dopamine (a neurotransmitter in the brain whose function is usually compromised in patients with Parkinson's disease). At any rate, this medication was approved by the Food and Drug Administration (FDA) in 1996.

Anyone with Parkinson's disease or who wants to prevent the spread of a viral infection (particularly influenza) should use this medicine. However, in order to prevent viral infection, the drug should be present before exposure to the virus just like a vaccine.

It is not a practical treatment for most viral infections even though it has been used to prevent Influenza A during flu season. Then again, even when given a day or two after the onset of flu symptoms, it should still be able to decrease the severity of the flu. Nowadays, it's being used to improve the symptoms of Parkinson's disease.

This medication should be administered once or twice every day with or without food. In case it causes the patient an upset stomach, take the next dose with food. When treating influenza, this medicine should be administered within 24 to 48 hours after the first flu symptoms appear and should be continued 24 to 48 hours after the disappearance of the flu symptoms.

Adamantamine is best used to prevent influenza. It must be administered as quickly as possible after flu virus exposure and should be continued for at least ten days. Elderly persons and people with reduced kidney function may need lower doses or less frequent doses of the medication.

The most common side effects include vomiting, nausea, nervousness, inability to sleep, loss of coordination, and dizziness. One out of twenty people have been reported to suffer from these symptoms after undergoing Adamantamine therapy. These side effects typically emerge after several days or even just a few hours of treatment. Less common side effects include discoloration of the eye, loss of appetite, constipation, diarrhea, slurred speech, amnesia, weakness, drowsiness, hallucinations, confusion, depression, nightmares, irritability, and headache. Seek immediate medical attention if you experience any of these symptoms.

Levodopa is more effective than Adamantamine in treating Parkinson's disease, but the latter possesses extra advantages when taken together with the former. You should also be aware that Adamantamine can alter the effects of alcohol and other sedatives such as the tricyclic class of antidepressants (Norpamin, Tofranil, and Elavil), the benzodiazepine class of anti-anxiety drugs (Ambien, Valium, Xanax, Klonopin, and Ativan), opiate agonists (Codeine, Vicodin, Dilaudid, and Percocet), certain antihypertensive medications (Catapres and Inderal), and certain antihistamines (Tavist, Atarax, Vistaril, and Benadryl). Combining Adamantamine with any of the above medications may cause dizziness upon standing, fainting, lightheadedness, or confusion for the patient.

Because this drug augments the actions of dopamine in the brain, other medications that block the effects of dopamine should be avoided while taking Adamantamine for Parkinson's disease treatment. Such medicines include phenothaizines like Mellaril (thioridazine) and Stelazine (triflupromazine), Haldol (halperidol), and Reglan (metoclopramide). Furthermore, using diuretics hydrochlorothiazide or Dyazide/Maxzide (triamterene) with Adamantamine can impede the kidney's ability to purge Adamantamine from your body. This can lead to increased levels of Adamantamine in your blood and increased risks for side effects.

It is currently not known how safe or deadly Adamantamine is for pregnant women and their unborn babies. Consult your doctor in order to determine whether or not Adamantamine's benefits to the pregnant mother outweigh its risks and disadvantages. Additionally, this drug has been proven to pass into breast milk in low concentrations. Even though it's not known how toxic Adamantamine is to infants, nursing mothers are discouraged from breastfeeding their babies while undergoing Adamantamine therapy. Again, consult your doctor for more details and recommendations.

Adamantamine has the following structural formula:

Chemical structure of adamantamine

• Molecular formula of adamantamine is C10H17N
• Chemical IUPAC Name is adamantan-1-amine
• Molecular weight is 151.249 g/mol
Adamantamine available : 100mg tablets

Generic name: Amantadine

Brand name(s): Adamantanamine, Adamantylamine, Adekin, Amantidine, Aminoadamantane, Endantadine, Mantadine, Symadine, Symmetrel

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