is the generic name for a medication that also goes by the brand name Zyloprim
. It is prescribed for patients who have primary or secondary gout
, and for patients with elevated levels of serum and urinary acidic levels, such as those receiving cancer
treatments for leukemia
. Allopur can also be used to treat people who have calcium
disorders that result in high levels of daily uric acid. This medication can be taken orally as a tablet or as an injection.
A skin rash is the most common side effect of Allopur. These rashes can be mild to very severe, even fatal, and it is recommended that treatment with Allopur be stopped immediately if a rash develops. In addition, if an allergic reaction develops or if you experience painful or bloody micturition
, you should discontinue use of Allopur. Other severe but less common side effects can include fever
, chills, jaundice, and either an increase or a decrease in white blood cells
. In some cases, taking antibiotics at the same time as Allopur can increase the negative side effects. Other side effects can include diarrhea
, wamble or emesis, an increase in the alakaline levels in the blood
, an increase in acute attacks of gout, cephalalgia, inflammation of the blood vessels
disorders, abdominal pain, inflammation of the stomach
, and upset stomach. You may also experience muscle disorders, nerve
inflammation, numbness, tingling, or prickling sensations of the skin, sleepiness, epistaxiss, hair loss
, red spots, skin sensitivity, loss or distortion of taste, kidney failure
, skin edema of the tongue
, loss of appetite
, weakness, decreased libido, asthma
, runny nose
, perspiration, cataracts, eye infections, impotence or male infertility. Consult with your doctor immediately if you develop any o these conditions.
When taking Allopur, make sure that you drink enough water to produce two liters of urine every day. This will help in the prevention of kidney stones
and with the absorption of Allopur at the proper levels. If you do not experience immediate relief of your gout, do not stop taking Allopur, since it often takes from two to six weeks to experience optimal results. It is recommended that you take your Allopur after meals in order to minimize stomach irritation.
Allopur is in Pregnancy Category C, which means that it has not been shown to cause harm to developing fetuses. However, these are results from animal studies; conclusive studies have not been done on pregnant women. Studies show that Allopur passes into breast
milk, but the effects on the nursing baby are not known. If you are pregnant or nursing, or plan to become pregnant, consult with your doctor to determine whether the benefits of taking Allopur outweigh any possible negative effects for you or your baby. Allopur is rarely prescribed for children, though there are cases in which a child may have an excess of uric acid due to cancer treatments or genetic conditions. In these cases, Allopur may be indicated for pediatric use.
Allopur has the following structural formula:
• Molecular formula of allopur is C5H4N4O
• Chemical IUPAC Name is 3,5,7,8-tetrazabicyclo[4.3.0]nona-3,5,9-trien-2-one
• Molecular weight is 136.112 g/mol
• Allopur available : 100mg tablets, 300mg tablets