is also known as Zyloprim
, prescribed for patients who have primary or secondary gout
, for patients with elevated levels of serum and urinary acidic levels, such as those receiving cancer
treatments for leukemia
, and also be used to treat people who have calcium
disorders that result in high levels of daily uric acid. Alositol is available in pill form or as an injection.
The most common side effect of Alositol is a rash that can be mild to very severe, even fatal. It is recommended that treatment with Alositol be stopped immediately if a rash develops. In addition, if an allergic reaction develops or if you experience painful or bloody micturition
, you should discontinue use of Alositol. Severe but less common side effects can include pyrexia, chills, jaundice, and either an increase or a decrease in white blood cells
. In some cases, taking antibiotics at the same time as Alositol can increase the negative side effects. Other side effects include diarrhoea, wamble or emesis, an increase in the alakaline levels in the blood
, an increase in acute attacks of gout, cephalalgia, inflammation of the blood vessels
ache, inflammation of the stomach, upset stomach, muscle disorders, nerve
inflammation, numbness, tingling, or prickling sensations of the skin, sleepiness, epistaxiss, baldness
, red spots, skin sensitivity, loss or distortion of taste, kidney failure
, skin edema of the tongue
, loss of appetite
, weakness, decreased libido, asthma
, rhinorrhea, perspiration, cataracts, eye infections, impotence or male infertility. See your doctor if you have any of these rare reactions.
While taking Alositol, drink enough water to produce two liters of urine every day to prevent kidney stones
and to help with the absorption of Alositol at the proper levels. If you do not experience immediate relief of your gout, do not stop taking Alositol, since it often takes from two to six weeks to experience optimal results. It is recommended that you take your Alositol after meals in order to minimize stomach irritation.
Alositol is in Pregnancy Category C, which means that it has not been shown to cause harm to developing fetuses. However, these are results from animal studies; conclusive studies have not been done on pregnant women. It has been determined that Alositol passes into breast
milk, but the effects on the nursing baby are not known. If you are pregnant or nursing, or plan to become pregnant or to nurse a baby, you should discuss it with your doctor to determine whether the benefits of taking Alositol outweigh any possible negative effects for you or your baby. Alositol is rarely prescribed for children, though there are cases in which a child may have an excess of uric acid due to cancer treatments or genetic conditions. In these cases, Alositol may be indicated for pediatric use.
Alositol has the following structural formula:
• Molecular formula of alositol is C5H4N4O
• Chemical IUPAC Name is 3,5,7,8-tetrazabicyclo[4.3.0]nona-3,5,9-trien-2-one
• Molecular weight is 136.112 g/mol
• Alositol available : 100mg tablets, 300mg tablets