is a prescribed medicament that affects a heartbeats rhythm. It is defined as an antiarrhythmic medicament. It is commonly administered to patients suffering from heart
rhythm disorders which can be life threatening when left unchecked. Brand names commonly attributed to Amiodarona include Pacerone
, and Cordarone I.V.
Amiodarona is used to treat ventricular fibrillation
or ventricular tachycardia
-- rhythm disorders of the ventricle
found in the lower portion of the heart in charge of moving blood
out of the organ. This medicament was discovered in 1961 but was only cleared for use in the United States in 1985.
Amiodarona is only used in life-threatening conditions due to its fatal side effects and severe allergic reactions
. Patients who are allergic to iodine or Amiodarona should not use this medicament. People who are suffering from heart conditions should first consult a doctor or physician before use. This is mainly used for patients who are suffering from serious arrhythmias of the heart; which includes atrial flutter, atrial fibrillation
, ventricular tachycardia, and ventricular fibrillation.
A patient must undergo extensive physical and medical examination by a doctor or physician before taking Amiodarona. Dosage depends on certain factors and requires that you tell your doctor about the current condition of your body to avoid fatal side effects.
Use of Amiodarona is done in the hospital where your condition is carefully monitored to detect side effects that could be fatal when left unchecked. Avoid self-medicament. This medicament should be taken with a full glass of water to properly dilute.
A person taking Amiodarona should consult or seek the help of a medical expert on the onset of allergic reactions to the medicament. This includes breathing problems, swelling
of the face, lips
, throat, or tongue
Common side effects attributed to Amiodarona include fast and slow pounding heartbeats, irregular heartbeat
and fainting, chest pains, flu-like symptoms, blurring of vision, short breathing, weight-loss, sudden body temperature change, increased sweating, numbness, burning sensation, nausea
and emesis, stomach
pain, pyrexia, clay-colored stools, and jaundice.
The above-mentioned symptoms might occur during the treatment or a few months after taking the medicament. It is very important to consult a doctor or physician if these appear to avoid fatal or life-threatening conditions.
Amiodarona is said to react to other medicaments containing cytochrome P450
isozyme, which include cyclosporine
, quinidine, simvastatin
, warafin, and other medicaments under the same family. The dose of these medicaments should be halved to avoid complications.
Patients suffering from lung
disorder (asthma), vision problems, thyroid disorder, liver
illness, blood pressure problems, electrolyte imbalance, or heart attachments may require dose adjustment as advised by your medical expert.
This medicament is in Category D Pregnancy. Women who are pregnant are advised not to take Amiodarona since it might harm the fetus. Inform your doctor of any change in your condition or if you become pregnant during treatment to avoid problems. Lactating mothers are advised to avoid breastfeeding since Amiodarona can be easily passed into breast
milk and cause further risk to the baby.
Amiodarona has the following structural formula:
• Molecular formula of amiodarona is C25H29I2NO3
• Chemical IUPAC Name is (2-butylbenzofuran-3-yl)-[4-(2-diethylaminoethoxy)-3,5-diiodo-phenyl]-methanone
• Molecular weight is 645.312 g/mol
• Amiodarona available : 200mg tablets