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Amiodarone

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Amiodarone

Amiodarone review





Amiodarone is a prescribed drug that affects a heartbeats rhythm. It is defined as an antiarrhythmic medication. It is commonly administered to patients who are suffering from heart rhythm disorders which can be life threatening when left unchecked. Brand names commonly attributed to amiodarone include Pacerone, Cordarone, and Cordarone I.V.

Amiodarone is used to treat ventricular fibrillation or ventricular tachycardia -- rhythm disorders of the ventricle found in the lower portion of the heart that is in charge of flowing blood out of the organ. This drug was discovered in 1961 but was only cleared for use in the United States until 1985.

Amiodarone is only used in life-threatening conditions due to its fatal side effects and severe allergic reactions. Patients who are allergic to iodine or amiodarone should not use this drug. People who are suffering from heart conditions should first consult a doctor or physician before use. This is mainly used for patients who are suffering from serious arrhythmias of the heart; which includes atrial flutter, atrial fibrillation, ventricular tachycardia, and ventricular fibrillation.

A patient must undergo extensive physical and medical examination by a doctor or physician before taking in amiodarone. Dosage depends on certain factors and requires that you tell your doctor about the current condition of your body to avoid fatal side effects from occurring.

Use of amiodarone is done in the hospital where your condition is carefully monitored to detect side effects that could be fatal when left unchecked. Avoid self-medication. This drug should be taken with a full glass of water to properly dilute

A person taking amiodarone should consult or seek the help of a medical expert on the onset of allergic reactions to the drug; this includes breathing problems, swelling of the face, lips, throat, or tongue; and hives.

Common side effects attributed to the use of amiodarone includes fast and slow pounding heartbeats, irregular heartbeat pattern, dizziness and fainting, chest pains, flu-like symptoms, blurring of vision, short breathing, weight-loss, sudden body temperature change, increased sweating, numbness, burning sensation, nausea and vomiting, stomach pain, fever, clay-colored stools, and jaundice.

The above-mentioned symptoms might occur during the treatment or a few months after taking the drug. Such is the case; it is very important to consult a doctor or physician when these appear to avoid fatal or life-threatening conditions.

Amiodarone is said to react to the actions of other medications containing cytochrome P450 isozyme, which drugs include cyclosporine, flecainide, quinidine, simvastatin, warafin, and other medications under the same family. The dosage of these medications should be halved to avoid complications.

Patients who are suffering from lung disorder (asthma), vision problems, thyroid disorder, liver disease, blood pressure problems, electrolyte imbalance, or heart attachments may require dosage adjustment as advised by your medical expert.

Category D Pregnancy is advised not to take amiodarone since it might harm the fetus. Inform your doctor for any change in your condition or sudden pregnancy during treatment to avoid problems. Lactating mothers is advised to avoid breastfeeding since amiodarone can be easily pass into breast milk and cause further risk to the baby.

Amiodarone has the following structural formula:

Chemical structure of amiodarone


• Molecular formula of amiodarone is C25H29I2NO3
• Chemical IUPAC Name is (2-butylbenzofuran-3-yl)-[4-(2-diethylaminoethoxy)-3,5-diiodo-phenyl]-methanone
• Molecular weight is 645.312 g/mol
Amiodarone available : 200mg tablets

Brand name(s): Amiodarona, Amiodarons, Amjodaronum, Cordarone, Labaz, Pacerone

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