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Amitriptyline

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Amitriptyline

Amitriptyline review





Amitriptyline is an effective and popular drug that battles depression. In medical terms it is called a tricyclic antidepressant drug. By inhibiting the serotonin and the noradrenaline reuptake in a persons body, Amitriptyline actually drives up the levels of those natural body chemicals so that the levels of depression decrease. It is usually sold under the labels Elavil, Tryptanol, Endep, Elatrol, Tryptizol, Trepiline, and Laroxyl. It is also has sedative effects, so it can be used to calm down people with anxiety and violent depression. Amitriptyline is typically used by doctors to treat clinical depression and depression in the elderly, however in some countries it is used to treat chronic migraines, chronic pain, carpal tunnel syndrome and insomnia. A medical study done in 2003 compared Amitriptyline with a control group of anti depressants, and almost 90% of the subjects had a more favorable response with Amtriptyline.

The side effects that people may experience while on this drug are dry mouth, drowsiness, dizziness, blurred vision, insomnia and weight gain. Because of the drowsiness and dizziness that people experience while taking this drug, most patients are encouraged not to drive or operate heavy machinery while on Amitriptyline. The side effects previously mentioned are the common side effects of the drug, but in some rare cases people may experience mania, hypotension, psychosis, and hepatic toxicity. If you experience any of these rare symptoms you should inform your doctor immediately.

People who have a history of seizures, liver diseases, blood diseases, hyperthyroidism, constipation and glaucoma should inform their doctor of their condition before taking Amitriptyline. Any of these diseases may hinder the medication. Patients with heart disease should be particularly careful because this drug causes abnormal rhythms in the heart. Patients with bipolar disorder might experience hypermaniac attacks if given Amitriptyline, doctors might want to adjust the dose or prescribe a different medication. The use of Amitriptyline hasn’t been cleared for pregnant women, and it also is passed through in breast milk so mothers should not nurse their children while they are on the drug.

Patients should also tell their doctor about any medication that they are taking before they try Amitriptyline. Medication like cisapride, monoamine oxidase inhibitors, Marplan, Nardil, Eldepryl, Emsam, Zelapar and Parnate have negative effects when combined with Amitriptyline. Any medication you are on might react badly with the Amitriptyline, even simple medication like sleeping pills, antihistamines, diet pills, herbal vitamins, or anything like that might react badly with Amitriptyline and be a cause for trouble. Giving your doctor a complete medical and drug history is a must.

Amitriptyline should only be taken as prescribed by your doctor. The tablets are small, white and odorless. They come in 10, 25, 50 and 70 mg tablets. The dosage for adults and the elderly is typically 25 to 150 mg daily depending on the severity of the condition being treated. It is very important to take the dosage recommended by your doctor, as too much might affect your mental health aversely and not positively.

Amitriptyline has the following structural formula:

Chemical structure of amitriptyline


• Molecular formula of amitriptyline is C20H23N
• Chemical IUPAC Name is 3-(10,11-dihydro-5H-dibenzo-[a,d]cyclohepten-5-ylidene)-N,N-dimethyl-1-propanamine
• Molecular weight is 277.403 g/mol
Amitriptyline available : 10mg tablets, 25mg tablets, 50mg tablets, 75mg tablets, 100mg tablets, 150mg tablets

Brand name(s): Adepress, Adepril, Amineurin, Amitid, Amitril, Amitriprolidine, Amitriptylin, Amitryptiline, Amitryptyline, Amytriptiline, Damilan, Damilen, Damitriptyline, Elanil, Elavil, Endep, Flavyl, Hexathane, Horizon, Lantron, Laroxil, Laroxyl, Lentizol, Pamelor, Proheptadiene, Redomex, Saroten, Sarotex, Seroten, Sylvemid, Triptanol, Triptilin, Triptisol, Tryptanol, Tryptizol

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