is a channel blocker, more specifically it is a calcium
channel blocker that is used mainly for chest pain
, also called angina, and high blood pressure
. Since calcium makes the arteries
contract and causes the arteries to become narrow, by blocking the calcium, Amlodipino helps the blood
flow into the heart
more smoothly. It also relaxes the muscle in the arteries to help the heart pump blood. Additionally, it reduces blood pressure and increases blood flow to other parts of the body. Chest pain is greatly reduced by the extra supply of blood to the heart. Usually the medicament of choice when treating high blood pressure and angina, Amlodipino helps the heart deal with high blood pressure by increasing the blood flow and relaxing the muscles, this way the heart doesn't have to work so hard.
Any prescription or non-prescription medicaments should be reported to your doctor before taking Amlodipino. Prescription medicaments for HIV
or acquired immunodeficiency syndrome, prostate
problems, seizures, fungal infections, bacterial infections
, or diuretics might be harmful to your body if taken with Amlodipino. Even herbal medicaments, natural supplements, large amounts of calcium, or even vitamins might affect the effectiveness of the medicament. Also, if the patient has ever had liver
illness or heart illness it might have left those organs weakened and thus more susceptible to the harmful Amlodipino effects. Inform your treating physician immediately if any of those illnesss have occurred. Patients who are already taking nitroglycerin
for angina don't have to stop taking it when Amlodipino is prescribed, nitroglycerin can be taken with Amlodipino without any harmful effects.
Some side effects that can occur while taking Amlodipino are: edema, dizziness
, upset stomach
, rashes, drowsiness, irregular heartbeat
of the hands and feet, and excessive tiredness. These are negligible side effects that are common with most medicaments. Patients must be careful not to drive after taken Amlodipino because the drowsiness that comes with taking the medicament might cause problems on the road. Some more serious side effects are severe chest pain, irregular heartbeat and fainting. If any of these occur then it is best to go to a hospital immediately.
No concrete evidence suggests that Amlodipino is harmful to pregnant women, but if you are pregnant or become pregnant during the treatment please inform your doctor as a safety measure. Only take Amlodipino if the benefits outweigh the probable danger to the fetus. A warning to mothers: researchers have not yet confirmed if the medicament is passed on through breast
milk, so as a precaution, nursing mothers should stop breastfeeding while on Amlodipino.
Amlodipino is commonly sold under the names Norvasc
and Istin. It is usually sold as pills in 5-10 mg tablets. Doctors usually prescribe 5mg at the beginning of treatment then gradually increase the dosage as they see fit. Amlodipino usually is in effect for a full 24 hours, so the dosage is typically daily. A tip when using this medicament is to have a low-sodium diet because it helps the medicament with its course of action.
Amlodipino has the following structural formula:
• Molecular formula of amlodipino is C20H25ClN2O5
• Chemical IUPAC Name is methylethyl2-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-6- methyl-1,4-dihydropyridine-3,5-dicarboxylate
• Molecular weight is 408.876 g/mol
• Amlodipino available : 2.5mg tablets, 5mg tablets, 10mg tablets