is a channel blocker, more specifically it is a calcium
channel blocker that is used mainly for chest pain
, also called angina, and high blood pressure
. Since calcium makes the arteries
contract and causes the arteries to become narrow, by blocking the calcium, Amlodipinum helps the blood
flow into the heart
more smoothly. It also relaxes the muscle in the arteries to help the heart pump blood. Additionally, it reduces blood pressure and increases blood flow to other parts of the body. Chest pain is greatly reduced by the extra supply of blood to the heart. Usually the medicament of choice when treating high blood pressure and angina, Amlodipinum helps the heart deal with high blood pressure by increasing the blood flow and relaxing the muscles, this way the heart doesn't have to work so hard.
Any prescription or non-prescription medicaments should be reported to your doctor before taking Amlodipinum. Prescription medicaments for Human immunodeficiency virus or Acquired immune deficiency syndrome, prostate
problems, seizures, fungal infections, bacterial infections
, or diuretics might be harmful to your body if taken with Amlodipinum. Even herbal medicaments, natural supplements, large amounts of calcium, or vitamins may alter the effectiveness of the medicament. Also, if the patient has ever had liver
disease or heart disease those organs may be weakened and thus more susceptible to the harmful Amlodipinum effects. Inform your doctor immediately if you have ever had any of those diseases. Patients already taking nitroglycerin
for angina may continue taking it when Amlodipinum is prescribed. Nitroglycerin can be taken with Amlodipinum without any harmful effects.
Some known side effects are: edema, dizziness
, upset stomach
, rashes, drowsiness, arrhythmia, swelling
of the hands and feet, and excessive tiredness. These are negligible side effects that are common with most medicaments. Patients must be careful not to drive after taken Amlodipinum because of the drowsiness that comes with taking the medicament. Some more serious side effects include severe chest pain, irregular heartbeat
and fainting. If any of these occur seek immediate medical attention.
No concrete evidence suggests that Amlodipinum is harmful to pregnant women, but if you are pregnant or become pregnant during the treatment please inform your doctor as a safety measure. Only take Amlodipinum if the benefits outweigh the probable danger to the fetus. A warning to mothers: researchers have not yet confirmed if the medicament is passed on through breast
milk, so as a precaution, nursing mothers should stop breastfeeding while on Amlodipinum.
Amlodipinum is commonly sold under the names Norvasc
and Istin. It is usually sold as pills in 5-10 mg tablets. Doctors usually prescribe 5mg at the beginning of treatment then gradually increase the dosage as they see fit. Amlodipinum usually is in effect for a full 24 hours, so the dosage is typically daily. A tip when using this medicament is to have a low-sodium diet because it helps the medicament with its course of action.
Amlodipinum has the following structural formula:
• Molecular formula of amlodipinum is C20H25ClN2O5
• Chemical IUPAC Name is methylethyl2-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-6- methyl-1,4-dihydropyridine-3,5-dicarboxylate
• Molecular weight is 408.876 g/mol
• Amlodipinum available : 2.5mg tablets, 5mg tablets, 10mg tablets