Amphicol review

Amphicol is a synthetic antibiotic that was introduced to the medical world in 1949. Since its inception, it has been found useful in treating bacterial infections caused by drug-resistant microorganisms. It has been widely used in many third-world countries because it is inexpensive compared to other antibiotics. In the United States Amphicol is used rarely due to its suspected role in the patient's increased risk for aplastic anemia. The only popular forms of Amphicol in the West are ointment and eye drops, used to reduce the symptoms of bacterial madras eye. In other countries, Amphicol is found useful in treating pneumonia and other bacterial infections that involve the eye and the prostrate gland.

Amphicol is administered by mouth, through an IV or topically. Oral Amphicol comes in 250mg capsules and 125mg/5ml liquid suspension while other forms come in a variety of doses. The typical dose is 50mg per kilogram of body weight distributed evenly in four dosing schedules. Severe conditions may require double the typical dose while newborns use only half since they do not metabolize the medicament as effectively.

Precautions must be taken before the administration of Amphicol. Young children, four years and below, using this medicament must be closely monitored. Amphicol may induce abnormal activity of blood cells, causing serious health problems. Since it is metabolized by the liver, any form of liver disorder should be discussed. Patients with liver or kidney diseases must receive a dose adjustment from their doctors to avoid any more damage. Pregnant and lactating women should not take Amphicol without the advice of their doctor. Amphicol may pose harm to the fragile bodies of fetuses and newborns.

If you are using other medicaments, inform your doctor about each one of them, including your vitamins. Some medicines react negatively to Amphicol and must not be taken together.

Amphicol did not boom in the US because of its harsh side effects. The most severe is aplastic anemia, a condition that is very rare yet fatal. It is not proven that blood count monitoring can prevent aplastic anemia but it has been observed to reduce the possibilities of complications connected with Amphicol treatment. Higher risk for aplastic anemia is found in patients who are using it orally. The patients at least risk are the ones using the eye drops form. Other known side effects of Amphicol include bone marrow suppression, childhood leukemia, and Gray Baby Syndrome.

To be safe while taking Amphicol, make sure that you are closely monitored by your doctor. Keeping a close watch on the progress of your symptoms and on the responses of your body to the medicament will help your doctor quickly resolve any issues. Never take this medicine without your doctor's advice and never use another person's or an old prescription for your current condition.

Amphicol has the following structural formula:

Chemical structure of amphicol

• Molecular formula of amphicol is C11H12Cl2N2O5
• Chemical IUPAC Name is 2,2-dichloro-N-[1,3-dihydroxy-1-(4-nitrophenyl)-propan-2-yl]-acetamide
• Molecular weight is 323.129 g/mol
Amphicol available : 250mg tablets

Generic name: Chloramphenicol

Brand name(s): Alficetyn, Ambofen, Amphenicol, Amseclor, Anacetin, Aquamycetin, Austracil, Austracol, Biocetin, Biophenicol, Catilan, Chemicetin, Chemicetina, Chlomin, Chlomycol, Chlora-Tabs, Chloramex, Chloramfenikol, Chloramficin, Chloramfilin, Chloramphenicole, Chloramsaar, Chlorasol, Chloricol, Chlornitromycin, Chlorocaps, Chlorocid, Chlorocide, Chlorocol, Chlorofair, Chloromax, Chloromycetin, Chloromycetny, Chloromyxin, Chloronitrin, Chloroptic, Chlorovules, Cidocetine, Ciplamycetin, Cloramfen, Cloramficin, Cloramicol, Cloramidina, Cloroamfenicolo, Clorocyn, Cloromisan, Clorosintex, Comycetin, Cylphenicol, Desphen, Detreomycin, Detreomycine, Dextromycetin, Doctamicina, Econochlor, Embacetin, Emetren, Enicol, Enteromycetin, Erbaplast, Ertilen, Farmicetina, Farmitcetina, Fenicol, Globenicol, Glorous, Halomycetin, Hortfenicol, Intramycetin, Isicetin, Ismicetina, Isophenicol, Juvamycetin, Kamaver, Kemicetina, Kemicetine, Klorita, Leukamycin, Leukomyan, Leukomycin, Levomicetina, Levomitsetin, Levomycetin, Liquichlor, Loromisan, Loromisin, Mastiphen, Mediamycetine, Medichol, Micloretin, Micochlorine, Micoclorina, Microcetina, Mychel, Mycinol, Normimycin V, Novochlorocap, Novomycetin, Novophenicol, Oftalent, Oleomycetin, Opclor, Opelor, Ophthochlor, Ophthoclor, Ophthocort, Ophtochlor, Optomycin, Otachron, Otophen, Owadziak, Pantovernil, Paraxin, Pedraczak, Pentamycetin, Pflanzol, Quellada, Quemicetina, Rivomycin, Romphenil, Ronphenil, Septicol, Sificetina, Sintomicetina, Sno-Phenicol, Stanomycetin, Synthomycetin, Synthomycetine, Synthomycine, Tevcocin, Tevcosin, Tifomycin, Tifomycine, Tiromycetin, Treomicetina, Tyfomycine, Unimycetin, Veticol, Viceton

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