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Amytriptiline

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Amytriptiline

Amytriptiline review





An effective and popular medication that battles depression is Amytriptiline. It is a tricyclic antidepressant and works by inhibiting the serotonin and the noradrenaline reuptake in a patient’s body. By doing this, Amytriptiline actually increases the levels of those natural body chemicals so that the levels of depression decrease. Typically sold under the names Elavil, Tryptanol, Endep, Elatrol, Tryptizol, Trepiline, and Laroxyl, it also has sedative effects, so it can be used to calm people with anxiety or violent depression. Most often used by physicians to treat clinical depression and depression in the elderly; however, in some countries it is used to treat chronic migraines, chronic pain, carpal tunnel syndrome and insomnia. A medical study done in 2003 compared Amytriptiline with a control group of anti depressants, and almost 90% of the subjects had a more favorable response with Amytriptiline.

The most common side effects of this medication include dry mouth, drowsiness, dizziness, blurred vision, insomnia and weight gain. Because of the drowsiness and dizziness patients experience while taking this medication, they are discouraged from driving or operating heavy machinery while taking Amytriptiline. The less common side effects include mania, hypotension, psychosis, and hepatic toxicity. If you experience any of these symptoms, seek immediate medical attention.

Patients with a history of seizures, liver diseases, blood diseases, hyperthyroidism, constipation and glaucoma need to advise their physician of these conditions before taking Amytriptiline since they may hinder the medication. Patients with heart disease need to be particularly careful. This medication can cause abnormal rhythms in the heart. Patients with bipolar disorder may experience hypermaniac attacks if given Amytriptiline. Physicians may want to adjust the dose or prescribe a different medication for those patients. The use of Amytriptiline has not been approved for pregnant or breastfeeding women. The medicine is passed through breast milk so mothers should not nurse their children while they are taking the medication.

Patients should talk with their physician about any and all medication that they are taking before they use Amytriptiline. Medications like cisapride, monoamine oxidase inhibitors, Marplan, Nardil, Eldepryl, Emsam, Zelapar and Parnate have negative interactions with Amytriptiline. Any medication you are taking may react negatively with Amytriptiline, even simple medications like sleeping pills, antihistamines, diet pills, or herbal vitamins. Make certain that your physician is aware of every medication you are taking, even those that are non-prescription, to be safe.

Amytriptiline should only be taken as prescribed. The tablets are small, white and odorless and come in 10, 25, 50 and 70 mg tablets. The dosage for adults and the elderly is usually 25 to 150 mg daily depending on the severity of the condition being treated. It is very important to take the prescribed dosage as too much of the medication may have negative affects on your mental health.

Amytriptiline has the following structural formula:

Chemical structure of amytriptiline


• Molecular formula of amytriptiline is C20H23N
• Chemical IUPAC Name is 3-(10,11-dihydro-5H-dibenzo-[a,d]cyclohepten-5-ylidene)-N,N-dimethyl-1-propanamine
• Molecular weight is 277.403 g/mol
Amytriptiline available : 10mg tablets, 25mg tablets, 50mg tablets, 75mg tablets, 100mg tablets, 150mg tablets

Generic name: Amitriptyline

Brand name(s): Adepress, Adepril, Amineurin, Amitid, Amitril, Amitriprolidine, Amitriptylin, Amitryptiline, Amitryptyline, Damilan, Damilen, Damitriptyline, Elanil, Elavil, Endep, Flavyl, Hexathane, Horizon, Lantron, Laroxil, Laroxyl, Lentizol, Pamelor, Proheptadiene, Redomex, Saroten, Sarotex, Seroten, Sylvemid, Triptanol, Triptilin, Triptisol, Tryptanol, Tryptizol

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