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Anakinra

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Anakinra

Anakinra review





Anakinra, or known by its brand name Kineret, is a man-made interleukin-1 receptor that blocks the effects of natural interleukin-1. It is commonly used for treating rheumatoid arthritis.

The natural IL-1 receptors in the human body attaches to the tissues surrounding the joints, as well as the cells around it and trigger an inflammation that results to arthritis. The synthetic IL-1 in Anakinra was designed to stop these from attaching. The U.S. Food and Drug Association approved the drug for use in 2001.

Anakinra (Kineret) should be used by people who are suffering from any forms of arthritis, or specifically rheumatoid arthritis. The synthetic IL-1 found in this drug stops the natural IL-1 in the human body to attach to receptors in tissues and cells around the joints in our body. This medication is mainly use for managing rheumatoid arthritis and to stop any progression of structural damage associated with the disease that is common in adults.

Considering that Anakinra is still a new drug in the market, the usual dosage includes 100mg subcutaneously once a day. Doctors might advise a reduction in the dosage for patients suffering from severe renal impairment. Taking in more than the prescribe dosage will not have any beneficial or adverse effect on your body. If you miss a dose, do not take double dosage; but continue the regular treatment the next day.

Clinical studies show that the duration for treatment is 24 weeks during the onset of rheumatoid arthritis before any signs of improvement can be seen. X-ray studies shows that 12-months of continuous treatment with Anakinra slow the progression of the disease.

Side effects commonly attributed to the use of Anakinra may include nausea, diarrhea, and slight abdominal pain going on and off throughout the treatment. There were reports that some patients under treatment with this medication show no sign of side effects at all.

Other significant side effects due to Anakinra may include infections in the upper respiratory tract, flu-like symptoms, and sinusitis. Infrequent reactions might include tuberculosis and pneumonia, but these are seen to be rare effects of the drug.

In rare cases, people who have allergic reactions to Anakinra may suffer from severe anaphylaxis. Skin rashes are also an allergic reaction to the medication. Patients are advised to consult a doctor or physician during the onset of these signs and symptoms of using Anakinra.

Anakinra is said to be a safe medication to use for treating rheumatoid arthritis. People who are allergic to Kineret are advised to consult a doctor and undergo a series of examinations to determine whether their body can handle the effects of the medication.

As with medications, it is essential to take the necessary precautions in taking in the drug despite its lack of side effects and allergic reactions to most body conditions. Check for the expiration date and make sure that it is property stored in a refrigerator and not exposed to sunlight or heat.

• Molecular formula of anakinra is C759H1186N208O232S10
• Chemical IUPAC Name is Human interleukin-1 receptor antagonist protein
• Molecular weight is 17257.6 g/mol
Anakinra available : 100mg tablets

Brand name(s): Kineret

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