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Apo-Bromocriptine

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Apo-Bromocriptine

Apo-Bromocriptine review





Apo-Bromocriptine, an ergoline derivative, causes vasoconstriction or a narrowing of the blood vessels. It is also a dopamine agonist that works by activating dopamine receptors in the brain for effective use against pituitary tumors and Parkinsons disease.

Apo-Bromocriptine is also used in the treatment of amenorrhea (a female condition where the menstrual period fails to occur). It is further used for infertility, abnormal breast milk discharge, hypogonadism (male reproductive disorder of the gonads), and acromegaly (excessive growth hormones in the body).

The medication works by lowering the body's levels of prolactin, the hormone primarily responsible for fertility and breast milk production in women. Since its prolactin content stimulates the immune system's T-lympocytes, Apo-Bromocriptine can be used to inhibit the immune system of patients undergoing organ transplants.

Apo-Bromocriptine also reduces the levels of hormonal growth in the body. It mimics the action of dopamine, a naturally occurring chemical in the body. This makes it ideal for the treatment of Parkinson's disease, a condition characterized by low dopamine levels in the brain, including its accompanying symptoms of stiffness, spasms, tremors and poor muscle control.

Other uses of Apo-Bromocriptine include treatment of cocaine addiction and neuroleptic malignant syndrome, a condition where tumors occur.

Before undergoing Apo-Bromocriptine therapy, inform your doctor if you are allergic to this or any other medication, particularly erythromycin, levodopa, hypertension medicines, medications for headaches or depression, decongestants, albuterol, terbutaline, oral contraceptives, tranquilizers, and any vitamin, mineral or herbal supplement.

Patients with kidney, heart or liver disease, a history of heart attack, angina (chest pain), any incidence of mental illness or circulatory problems in the fingers during cold weather should tell their doctor before starting Apo-Bromocriptine treatment. These conditions may require a lower dosage of medication and constant monitoring during the course of treatment.

The effects of Apo-Bromocriptine are negated by phenothiazine medications like chloropromazine, thioridazine, mesoridazine, perphenazine and fluphenazine. These may necessitate an increase in Apo-Bromocriptine dosage.

Female patients should let their doctor know if they are pregnant, plan to become pregnant or become pregnant during treatment. Although Apo-Bromocriptine has been classified by the FDA in pregnancy Category B, which makes it unlikely to be harmful to the fetus, Apo-Bromocriptine should only be taken if the benefits far outweigh any potential risks it may pose to an unborn baby. As Apo-Bromocriptine can stop lactation, breastfeeding is not encouraged while undergoing treatment.

Women taking Apo-Bromocriptine for amenorrhea, and who do not wish to become pregnant, will need to use a different method of birth control other than oral contraceptives, as this method may cause delays in the menstrual period.

Since Apo-Bromocriptine can cause low blood pressure and drowsiness, patients taking this medication should refrain from sitting up or rising abruptly, driving a vehicle, operating any type of machinery or consuming alcoholic beverages, which may exacerbate dizziness and lightheadedness.

If patients are taking the medication for the treatment of high levels of prolactin that are caused by tumors, they should let their doctor know immediately if they start experiencing constant watery nasal discharges.

Although Apo-Bromocriptine can cause mild temporary side effects as the body adjusts to the medication, patients should inform their doctor if they start to experience severe and persistent side effects like dizziness, stomach upset, headaches, nasal congestion, fatigue, insomnia, vomiting or constipation. It may become a cause for concern if the patient starts to exhibit tingling and swelling of feet or ankles, bloody vomit, fainting, nightmares, fast or irregular heartbeat, confusion, involuntary twitching movements, vision changes, depression, and a watery nasal discharge. These conditions warrant immediate medical attention.

Apo-Bromocriptine is manufactured under the brand name Parlodel, and is available by prescription in 2.5mg round white tablets and 5mg white caramel capsules. It should be taken as directed by the doctor, usually several times a day with meals, depending on the patient's condition. Patients are advised not to suddenly stop taking Apo-Bromocriptine without talking with their doctor, as immediate cessation of the medication may only make their condition worse.

Apo-bromocriptine has the following structural formula:

Chemical structure of apo-bromocriptine


• Molecular formula of apo-bromocriptine is C32H40BrN5O5
Apo-bromocriptine available : 5mg capsules, 2.5mg tablets

Generic name: Bromocriptine

Brand name(s): Alti-Bromocriptine, Bagren, Parlodel, Pravidel

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