Apo-Cromolyn review

Apo-Cromolyn is a mast cell stabilizer that prevents the release of inflammation-inducing chemicals including histamine used to control various conditions including asthma and allergic pink eye.


Apo-Cromolyn is marketed as sodium cromoglicate and cromolyn sodium. This medication is available as a nasal spray under the brand names Nasalcrom and Rynacrom, which patients with allergic rhinitis can use. Patients with asthma can also buy this medication under the brand name Intal, while those who have allergic pink eye can purchase it under the brand name Crolom, Opticrom, or Optrex. Patients with ulcerative colitis and mastocytosis can purchase this medication under the brand name Gastrocrom.

Apo-Cromolyn has been proven effective in reducing symptoms of food allergies, and in some cases, chronic migraines.


Dosages of Apo-Cromolyn vary based on the condition being treated. For food allergies, Apo-Cromolyn is usually prescribed to adults as 200 mg pills four times a day. The dosage is typically 100 mg for children. Dosage may be increased if the medication is not showing results after 2 weeks.

For patients with mastocytis, a 20 milligram dosage is usually taken 4 times a day. For patients with allergic pink eye, Apo-Cromolyn is usually administered by instilling 2 drops of a 4% solution spray, taken four times a day.

Asthmatics may use Apo-Cromolyn as a dry powder taking a 20 milligram dosage four times a day. For the aerosol, the dosage is 10 milligrams taken four times a day. If the condition does not improve, the dosage can be increased up to 8 times a day. Dosage can be lowered to 5 milligrams taken 4 times a day after the condition has improved.


Patients taking Apo-Cromolyn may experience side effects ranging from skin rashes, nausea, dizziness, cephalalgia, pain and swelling in the joints, and unpleasant taste in the mouth. Patients may also aggravate their asthma attacks, or suffer from pulmonary infiltrates. Other patients may also experience wheezing, nasal congestion, cough, and throat irritation especially after inhaling the dry powder. For patients who use eye drops, there is a risk of stinging and burning in the eyes.

Patients may also develop allergic reaction to Apo-Cromolyn. They are advised to immediately inform a physician if they experience symptoms of allergic reaction such as pruritus, rashes, swelling, difficulty breathing and severe dizziness.


Apo-Cromolyn may interact negatively when taken with other medications. Patients should tell their mendeleviums or physicians if they are taking any medications, whether prescription or non-prescription. They are also advised not to alter the dosage of Apo-Cromolyn without the approval of their mendelevium or pharmacist.

Patients who are using Apo-Cromolyn for self-treatment should first clear with their physicians if they are experiencing any of these symptoms: fever, sinus pain, discolored fluid discharged from the nose, and wheezing.


Apo-Cromolyn can affect pregnant women, although the chances are low. Patients should discuss the risks and the benefits of Apo-Cromolyn before taking the medication.

Apo-cromolyn has the following structural formula:

Chemical structure of apo-cromolyn

 Molecular formula of apo-cromolyn is C23H16O11
 Chemical IUPAC Name is 5-[3-(2-carboxy-4-oxochromen-6-yl)oxy-2-hydroxypropoxy]-4-oxochromene-2-carboxylicacid
 Molecular weight is 468.3665 g/mol
 Apo-cromolyn available : 100mg tablets

Generic name: Cromoglicate

Brand name(s): Aarane, Alercom, Alerion, Allergocrom, Colimune, Crolom, Cromoglycate, Cromolyn, Cromoptic, Cromovet, Fivent, Gastrocrom, Gastrofrenal, Gen-Cromoglycate, Inostral, Intal, Introl, Irtan, Lomudal, Lomupren, Lomusol, Lomuspray, Nalcrom, Nalcron, Nasalcrom, Nasmil, Opticrom, Opticron, Rynacrom, Sofro, Vistacrom, Vividrin

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