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Axert

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Axert

Axert review





Axert, also known by the trade names of Amotriptan and Almogran, belongs to a class of medicaments called 5-HT1 agonists. It is a medicament that eases the pain connected with migraines by narrowing the skin edema blood vessels around the brain. This medicine is mostly available in tablet form and contains a water-soluble white to slightly yellow powder.

This prescription medicament is mainly used by patients to manage migraines, although it can be also used to treat hepatitis and renal impairment. An Axert- or Almogran-brand product usually has 6.25 to 12.5 milligrams worth of Axert in each tablet.

Controlled clinical tests prove that single doses of 6.25 milligrams and 12.5 milligrams of Axert tablets were very successful in acute migraine therapy for adults, with the heavier 12.5 milligram dose being the more effective of the two dosages. Take note that individual response to the medicament is on a case-by-case basis, so dosage will depend on the patient himself. Consult your doctor or pharmacist in order to get a proper Axert prescription.

In any case, the maximum daily dose of Axert for hepatitis treatment shouldn't go beyond 12.5 milligrams over a twenty-four hour period, while a dose of 6.25 milligrams should be urinary tract infectionlized for the initial dose. Equally, the maximum daily dose for patients with severe renal impairment should also not exceed 12.5 milligrams per day and the staReverse transcriptase inhibitorsng dose of 6.25 milligrams should also be used.

The most typical side effects during Axert treatment are dry mouth, paraesthesia, cephalalgia, somnolence, and nausea. Long-term, open-label research for patients who were allowed to treat multiple attacks for up to one year have revealed that 5% of the patients (or 63 of 1,347 patients) withdrew from continued therapy because of the harshness of the side effects.

Life-threatening cardiac events like coronary artery vasospasm and heart attack have happened in patients undergoing Axert therapy even though they are exceedingly rare and most have been found in patients with risk factors prognostic of CAD (coronary artery disease). Other side effects reported in relation with medicaments of this class include ventricular fibrillation, ventricular tachycardia, heart attack, transient myocardial ischemia, and coronary artery vasospasm.

Severe disturbances in cardiac rhythm and even death have occurred within a few hours following the administration of this medicament and other 5-HT1 agonists. Of course, the incidence of this paReverse transcriptase inhibitorscular side effect is very rare, especially when you consider the large number of patients using 5-HT1 agonists that have not suffered from these consequences. If you have a history of uncontrolled high blood pressure, cardiovascular ischemia, stroke, or heart attack, notify your doctor immediately.

Moreover, certain medicaments taken along with Axert can result in potentially fatal medicament interactions. As such, you should not take MAO inhibitors like tranylcypromine, selegiline, procarbazine, phehelzine, linezolid, and furazolidone for at least two weeks before or after taking this medicament. You should also not take any other triptan-type migraine medicaments like sumatriptan and zolmitriptan or ergot-type medicaments like methysergide, ergotamine, and dihydroergotamine within 24-hours of taking this medicament.

It is currently unknown whether or not Axert can pass into human milk, so a nursing mother should avoid breastfeeding her child altogether while taking this medicament. She should also consult her doctor for more information. Moreover, the effectiveness and safety of Axert in children have not been established, so this medicament is not advised for patients below eighteen years of age.

Caurinary tract infectionon should be exercised by elderly patients taking this medicament; a lowered dose may be prescribed to them depending on their body's current cardiac, renal, and hepatic function. As always, doctor consultation is important.

Axert has the following structural formula:

Chemical structure of axert


• Molecular formula of axert is C17H25N3O2S
• Chemical IUPAC Name is N,N-dimethyl-2- [5-(pyrrolidin-1-ylsulfonylmethyl)- 1H-indol-3-yl]-ethanamine
• Molecular weight is 335.465 g/mol
Axert available : 6,25mg tablets and 12,5mg tablets

Generic name: Almotriptan

Brand name(s): Eletriptan

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