Balsalazida review

Balsalazida is an anti-inflammatory medication used in treating inflammatory bowel diseases like active colitis ulcerosa. Balsalazida releases mesalamine once it reaches the large intestines (which are believed to be the active sites for colitis ulcerosa) and reduces skin edema within the lining of the intestines in order to allow it to heal. It can then help further reduce recurrence of the symptoms. It is a prescription medication marketed as Colazal in the United States and Colazide in the United Kingdom - both brands come in 750 mg capsules.

Balsalazida is used to treat colitis ulcerosa as it alleviates symptoms like diarrhoea, stomach pain and rectal bleeding. It may be helpful in treating Crohn's colitis and lymphocytic or microscopic colitis as well. It is prescribed to patients 5 years old and older.

The recommended adult dose is 3 capsules a day at evenly spaced intervals. This treatment usually will last about 8 weeks or until symptoms improve. The child's dose may consist of only a single capsule per day but will vary based on the child and the symptoms. The treatment may last as long as 12 weeks but know studies have been conducted to verify benefits of extending the treatment.

An alternative way to take Balsalazida is to open a capsule and sprinkle the contents onto a tablespoon of applesauce before swallowing the mixture immediately. The contents may need to be chewed especially if the contents of the capsules are in larger fragments. Color variation may occur and teeth staining may be experienced when Balsalazida is consumed like this.

Take skipped dose as soon as possible and resume treatment as scheduled. Do not take twice the dose to compensate for a missed dose.

Some common side effects from taking Balsalazida include cephalalgias, insomnia, nausea and emesis, stomachache, diarrhoea, cold-like symptoms and joint pain. If any of these become particularly bothersome then consult your doctor.

More serious side effects include aggravated colitis symptoms such as rectal bleeding, stomach cramps and bloody stools. Some may even experience paleness and easy bruising. Jaundice, passing dark urine and bloating may also arise rarely. If any of these symptoms occur, immediately discontinue the use of Balsalazida and consult your doctor.

Consult your doctor before taking this medication and inform them if you are pregnant, plan to become pregnant or breastfeeding. It may not be recommended to take this medication while pregnant.

Kidney and liver problems may pose complications while taking Balsalazida, so inform your doctor about these conditions as well. Other conditions that should be reported to your physician include asthma, stomach ulcers or duodenal ulcers (as opposed to those in the colon), and blood conditions. Inform them of any medication you are currently taking, including methorexate and digoxin. Doctors will also want to know if you have experienced allergic reactions to Balsalazida or other salicylates such as aspirin or mesalazine. Hypersensitivity or allergic reactions may include anaphylaxis, tightening of the airways and skin reaction such as rashes, but other symptoms may also manifest and are not limited to those mentioned.

Balsalazida has the following structural formula:

Chemical structure of balsalazida

• Molecular formula of balsalazida is C17H15N3O6
• Chemical IUPAC Name is 5-[4-(2-carboxyethylcarbamoyl)phenyl]diazenyl-2-hydroxy-benzoic acid
• Molecular weight is 357.318 g/mol
Balsalazida available : 750mg tablets

Generic name: Balsalazide

Brand name(s): Balsalazido, Balsalazidum, Carbadox, Colazal

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