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Benclamin

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Benclamin

Benclamin review



buy Benclamin Buy Benclamin
Benclamin belongs to a class of drugs known as sulfonylureas. Sulfonylureas are a type of anti-diabetic drugs used in the management of type 2 diabetis mellitus, or the adult-onset diabetis. The main action of the drugs is to increase the release of insulin in the beta cells found in the pancreas.

Benclamin, also known as glyburide, is indicated for used in the treatment of type 2 diabetes. The drug is administered coupled with diet, exercise and insulin therapy. Benclamin is marketed under various trade names: Micronase, Glynase, and Diabeta in the United States and Euglucon, Semi-Daonil, and Daonil in the United Kingdom. It is also available under the name Benclamin, which is sold in combination with metformin.

Benclamin is sold in formulations of 1.25 mg, 2.5 mg and 5 mg. The recommended initial starting dosage for Benclamin therapy is at 2.5 to 5 mg daily, taken with breakfast or the first main meal of the day. However, for patients sensitive to hypoglycemic drugs, a lower dosage should be used, preferably at 1.25mg daily. Raising the dosage depends on the patient’s response to the drug therapy.

Common side effects that result from the use of Benclamin include allergic reactions to the drug, of which these symptoms may include: difficulty in breathing, swelling of the lips, mouth, or face, rashes and hives.

Elevated or lowered blood sugars, and complications arising from these conditions (shaking, headaches, cold skin and sweat, and anxiety) are also noted side effects of the drug. Hypoglycemia or low blood sugar may occur if taking Benclamin with missed or delayed meals. Too much exercise may also aggravate some drug effects and produce diarrhea, vomiting, and nausea.

Elevated blood sugar levels or hyperglycemia may also occur if not enough dosage of the drug is taken, or if the patients eat more than usual or exercises less. Symptoms include increase in thirst, hunger and urination.

Benclamin is contraindicated in patients with a known history of hypersensitivity to the drug, or other anti-diabetic drugs. It is also contraindicated in patients with diabetic ketoacidosis, with or without coma, and is also contraindicated in patients with Type I Diabetis Mellitus.

Patients with known kidney, thyroid or liver diseases and with serious infections or illnesses that may need surgery, may not be able to take the drug, or may require special dosages.

Caution is advised when administering the drug to geriatric patients as older people may have stronger reactions to the drug, and thus, may require reduced doses.

The administration of oral hypoglycemic drugs in general was reported to have a relationship with the increase in deaths caused by heart failure. Caution is to be advised when administering the drug to patients with cardiovascular impairment.

It is not known whether Benclamin causes harm to the unborn baby. For treating pregnant patients with diabetis, it is usually insulin that used as a primary drug of choice. The doctor must always be consulted prior to the use of the drug, especially if you are pregnant or planning to get pregnant. As other drugs may be excreted in breast milk, nursing mother must always weigh the potential benefits of the drug against the risks it may bring to the nursing mother and the baby.

Benclamin has the following structural formula:

Chemical structure of benclamin


• Molecular formula of benclamin is C23H28ClN3O5S
• Chemical IUPAC Name is 5-chloro-N-[2-[4-(cyclohexylcarbamoylsulfamoyl)phenyl]ethyl]-2-methoxybenzamide
Benclamin available : 1.25mg tablets, 2.5mg tablets, 5mg tablets

Generic name: Glyburide

Brand name(s): Abbenclamide, Adiab, Azuglucon, Bastiverit, Betanase, Calabren, Cytagon, Daonil, Debtan, Dia-basan, Diabeta, Diabiphage, Dibelet, Duraglucon, Euclamin, Euglucan, Euglucon, Euglykon, Gen-Glybe, Gewaglucon, Gilemal, Glamide, Glibadone, Gliban, Gliben, Glibenbeta, Glibenclamida, Glibenclamide, Glibenclamidum, Glibenil, Glibens, Glibesyn, Glibet, Glibetic, Glibil, Gliboral, Glicem, Glidiabet, Glimel, Glimide, Glimidstata, Glisulin, Glitisol, Glubate, Gluben, Gluco-Tablimen, Glucobene, Glucohexal, Glucolon, Glucomid, Glucoremed, Glucoven, Glyben, Glybenclamide, Glybenzcyclamide, Glycolande, Glycomin, Glynase, Hemi-Daonil, Hexaglucon, Humedia, Lederglib, Libanil, Lisaglucon, Malix, Maninil, Med-Glionil, Melix, Micronase, Miglucan, Nadib, Neogluconin, Normoglucon, Novo-Glyburide, Orabetic, Pira, Praeciglucon, PresTab, Prodiabet, Renabetic, Sugril, Suraben, Tiabet, Yuglucon

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