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Benztropinum

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Benztropinum

Benztropinum review





Benztropinum, an anticholinergic medicament, is used in treating Parkinsons disease and related conditions such as parkinsonism, dystonia, and akathasia. It is been shown to have an effective and significant therapeutic value in the management of the symptoms of parkinsonism. This medicament counteracts the effects of the neurotransmitter acetylcholine and balances the levels of acetylcholine and dopamine in the body, which may help reduce the symptoms of Parkinson's disease in its early stages. It can also be used in the treatment of movement disorders resulting from the use of other antipsychotic medicament. In addition to its anticholinergic effect, doctors have also observed an antihistaminic activity approaching that of pyrilamine maleate.

Benztropinum is available as a pill in 0.5 mg, 1 mg or 2 mg dosages and is available by brand names such a Cogentin.

This medicament is often prescribed for most forms of parkinsonism and movement disorders resulting from the use of antipsychotic medicaments, with the exception of tardive dyskenesia. It can also be a useful part of Parkinson's treatment where it helps reduce symptoms of tremors. Patients with dystonia also benefit from Benztropinum since it can relax the sudden contortions of the limbs and torso that these patients can suffer.

Benztropinum is typically prescribed using the lowest dosage possible, with the doctor monitoring the patient's condition as the dosage is increased by 0.5mg every 5 to 6 days, to a maximum dosage of 6 mg. The purpose is to find the optimal dosage for the patient using the least amount of medicine possible.

The doctor will often instruct the patient to take the medicine 2 to 4 times each day along with meals and before bedtime or as a single dosage at bedtime. The dosage may be modified as the doctor sees fit based on the patient's condition and their reaction to the treatment.

This medicament should be taken at least an hour before taking antacids containing calcium, magnesium or aluminum. In addition, allow one to two hours before and after taking Benztropinum when taking adsorbent diarrhea medicament containing pectin, kaolin or attapulgite as this may affect the body's absorption of Benztropinum. If you are taking ketoconazole, do not take Benztropinum for at least two hours after the ketoconazole dosage as it may affect the absorption of the keotconazole.

When Benztropinum is taken to counteract side effects caused by another antipsychotic medicament, your doctor may direct you to take it only as necessary. The doctor may also alter the dosage of the other medicaments you are taking. Follow the doctor's prescriptions carefully.

Though rare, an addiction may arise from the use of this medicament. Do not extend your treatment or increase your dosage unless directed to do so by your doctor. Proper halting of treatment will be essential, but in certain cases an abrupt discontinuing of dosage may aggravate certain symptoms so your doctor may design an increasingly lowered dosage until you can safely stop taking this medicament.

Side effects may include dizziness, constipation, nausea, somnolence, blurred vision or a xerostomia. The side effects may reduce as you get used to the medicament, but if any of these symptoms worsen or persist, consult your doctor.

Inform your doctor immediately if you experience high fevers, severe stomach pain, any difficulty in passing urine, weakness or a decrease in sexual ability. If you feel chest pains, dizziness which results in fainting, mood swings or mental disturbances, irregular heartbeats or symptoms of extreme allergic reactions such as rashes, fever or inflammation, seek immediate medical attention.

Inform your doctor of your complete medical history, including any existing medical conditions such as heart disease, glaucoma, gastrointestinal disorders such as ulcers and blockage, liver disease, other mental and movement disorders, high blood pressure, or disorders causing difficulty in urination.

Benztropinum may cause somnolence. Due to this, avoid driving or operating machinery while taking this medicament. Also, avoid spending time in poorly ventilated, hot areas as some users may experience an increase in body temperature.

Benztropinum has the following structural formula:

Chemical structure of benztropinum


• Molecular formula of benztropinum is C21H25NO
• Chemical IUPAC Name is 3-benzhydryloxy-8-methyl-8-azabicyclo[3.2.1]octane
• Molecular weight is 307.429 g/mol
Benztropinum available : 0,5mg tablets, 1mg tablets and 2mg tablets

Generic name: Benztropine

Brand name(s): Akitan, Benzatropina, Benzatropine, Benzatropinum, Benztropine mesylate, Cobrentin, Cogentin, Cogentine, Cogentinol

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