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Bicalutamide review by Medicalook.com
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Bicalutamide is a nonsteroidal type of antiandrogen. It is an oral hormone treatment that may be used as either a part of a program to cure advanced prostate cancer (often with medical or surgical castration) or as monotherapy for the early stages of the same sickness. It does this by both blocking the action of testosterone and by slowing or preventing the emergence of cancer cells. Bicalutamide, on occasion, has been prescribed for other uses; however, this is rare and is always solely the call of the physician. Its popular brand names include Casodex, Cosudex, and Kalumid.
Bicalutamide is not safe for use for children. Physicians very rarely prescribe it. It is also not to be used by women, especially those who have a chance of becoming pregnant soon. It is potentially harmful to both mother and fetus. While Bicalutamide has been used in medical trials for the treatment of ovarian cancer, nothing has been confirmed yet, and it still remains unadvisable for women to take it.
Doctors should also be informed of any medical allergies or history of liver disease before treatment is started to prevent any adverse reactions.
Bicalutamide is an orally ingested drug which comes in the form of a soluble off-white powder. It may be taken with or without food, but it is always prudent to avoid ingesting the drug with an empty stomach to avoid any form of discomfort. Bicalutamide is often taken once or twice a day, but the doctor’s prescription should always be followed. The drug should be taken at the same time each day. If a dosage is missed, take it as soon as you remember, but do not take more than the prescribed amount at one time to compensate. In case of accidental overdosage, immediately seek medical attention.
Avoid combining Bicalutamide with other types of drugs, especially anticoagulants – more commonly known as blood thinners – and aspirin. Men should also try as much as possible to avoid impregnating anyone while taking Bicalutamide, as it may have harmful effects on the fetus. A potential sleep-inducer, Bicalutamide would make it unsafe to try unsafe tasks such as driving until you are absolutely sure of its effect on you.
Doctors do not usually prescribe any special diets for those taking the drug.
Studies have shown that sperm production may be stopped by Bicalutamide, but nothing permanent is supposed to be caused by the drug. Milder side effects include dizziness, diarrhea, impotence, headaches, and hot flashes. Unless these are really severe, however, there is no need to worry. Only contact your physician otherwise.
If you experience any of the following symptoms, however, set an appointment with your doctor immediately: jaundice, dark urine, vomiting, changes in vision, flu symptoms, and pneumonia.
Bicalutamide must be stored at room temperature at a dry location in the container it was originally given to you in. Once past the expiry date, get rid of it immediately.
Bicalutamide has the following structural formula:
• Molecular formula of bicalutamide is C18H14F4N2O4S
• Chemical IUPAC Name is N-[4-cyano-3-(trifluoromethyl)phenyl]-3-(4-fluorophenyl)sulfonyl-2- hydroxy-2-methyl-propanamide
• Molecular weight is 430.374 g/mol
• Bicalutamide available : 50mg tablets
Brand name(s): Casodex
Review published on: 08 March 2008
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