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Calcijex

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Calcijex

Calcijex review





Calcijex, or dihydroxycholecalciferol, is an active synthetic form of Vitamin D that enables the body to absorb greater amounts of calcium and phosphate from the kidneys and gastrointestinal tract. It aids the body in making the most of the calcium coming from ingested food and other supplements, as well as stimulates the release of calcium and phosphate that are stored in the bones.

Calcijex belongs to a group of medications classified as vitamins. It is usually prescribed to patients undergoing chronic renal dialysis for kidney disease, hypoparathyroidism, a condition characterized by a decreased function of the parathyroid glands (glands in the neck which control calcium levels in the blood), and hypocalcemia, which causes nerve and muscle spasms due to low blood calcium.

Calcijex is also used in the treatment of secondary hypoparathyroidism and metabolic bone disease secondary to kidney failure. People with calcium deficiencies and those who suffer from bone diseases like osteoporosis can benefit from taking regular doses of Calcijex. Patients suffering from psoriasis, a skin disease, are sometimes prescribed a topical form of Calcijex.

Calcijex has also been used to treat rickets (a Vitamin D deficiency in children characterized by a softening and weakening of the bones), osteomalacia (soft and weakened bones due to adult Vitamin D deficiency), and familial hypopohosphatemia (inability of the body to metabolize Vitamin D). In some cases, it is also used to increase the calcium blood levels in premature infants.

Patients should inform their doctor if they are allergic to Calcijex or Vitamin D in other forms. Before starting Calcijex, patients should inform their doctor of any prescription or over-the-counter medication, including vitamin, mineral or herbal supplements they may be taking. This is to determine whether these may cause any adverse interactions when taken with Calcijex.

People suffering from kidney disease or any liver ailment should tell their doctor of their condition. They should also inform their doctor if they have recently undergone surgery. Women who are pregnant, plan to become pregnant, or become pregnant during treatment should advise their doctor of their condition. The FDA has classified Calcijex in pregnancy category C, which means it is still not known whether it may be harmful to the unborn baby. Breastfeeding mothers should refrain from breastfeeding while taking this medication.

There are some medications that can result in ill effects when taken with Calcijex. Some of these medications include digoxin, a medication for congestive heart failure; antacids containing magnesium, cholestyramine, which reduces blood cholesterol levels; orlistat, a weight loss medication; thiazide diurectics, which reduce amount of water in the body, and mineral oil. Patients taking these medications are advised not to take Calcijex, or to have a dosage adjustment and special monitoring by their doctor during the course of treatment.

Calcijex can cause some side effect during treatment. The primary adverse reaction is hypercalcaemia, a condition in which blood calcium levels are elevated. It is characterized by nausea, vomiting, constipation, anorexia, apathy, headaches, sweating and frequent urination.

Other rare but serious symptoms of Calcijex include weakness, dry mouth, muscle and bone pain, a metallic taste in the mouth, weight loss, thirst, frequent or painful urination, changes in vision, fever or chills, pale and fatty stools, jaundice, loss of libido, irregular heartbeat, runny nose, and breathing difficulties. Patients who experience these symptoms may have accumulated excessive calcium in their body and should call their doctor immediately.

Calcijex comes in 0.25 mcg. light orange oval soft gel capsules, 0.5 mcg. dark orange oblong soft gel capsules, and a 1 mcg./ml. oral solution . It is distributed under the brand names Rocaltrol (Roche), Calcijex (Abbot), and Decostriol.

Calcijex should be taken according to the doctor’s directions, usually swallowed whole with a full glass of water, once a day or every other day. The exact dosage for Calcijex suspension should be measured using a measuring cup, dropper or spoon.

Calcijex will achieve its optimum effect through a balanced diet containing the right amounts of calcium. If too much calcium is derived from food, the patient will start to experience some serious side effects. Too little calcium from food will result in canceling out the beneficial effects of Calcijex.

Calcijex has the following structural formula:

Chemical structure of calcijex


• Molecular formula of calcijex is C27H44O3
• Chemical IUPAC Name is 5-[2-[1-(6-hydroxy-6-methyl-heptan-2-yl)-7a-methyl-2,3,3a,5,6,7- hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidene-cyclohexane-1,3-diol
• Molecular weight is 416.636 g/mol
Calcijex available : 0.25mcg capsules, 0.5mcg capsules

Generic name: Calcitriol

Brand name(s): Rocaltrol

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