Calepsin review

Calepsin, also known as CBZ, is an anticonvulsant medication and a mood-stabilizing agent. It acts by decreasing the amount of abnormal excitement in the brain and is used for epilepsy and the treatment of bipolar disorders.

Calepsin is effective in controlling seizures by blocking certain brain impulses. It is also used for ADD (Attention Deficit Disorder), ADHD (Attention Deficit Hyperactive Disorder), and schizophrenia (a psychiatric condition).

Used by itself or combined with other seizure medications, Calepsin is used to calm manic episodes where the patient exhibits extreme mood swings, mixed episodes of mania and depression, and other abnormal moods.

Calepsin can also be used for the treatment of trigeminal neuralgia, a condition that causes severe pain in the facial nerves. Calepsin shifts nerve impulses from the affected facial nerves to ease the pain that accompanies this condition.

Calepsin is also prescribed for mental diseases like depression, post-traumatic stress disorder, withdrawal from medication and alcohol addictions, restless legs syndrome, diabetes insipidus and a children's disease called chorea.

Patients with a history of bone marrow suppression, porphyria (a blood disorder) and atrioventricular block (a severe heart block problem) should not take Calepsin as the medication will only make their conditions worse. Patients taking antidepressant medications like amitriptyline (Elavil), desipramine (Norpramin), imipramine (Trofranil), or nortriptyline (Pamelor) should refrain from taking Calepsin to prevent adverse interactions between the medications.

Other medications with negative interactions include cold and allergy medicines, pain relievers, sleeping pills, muscle relaxants, antidepressants like isocarboxazid (Marplan) and phenelzine (Nardil), and anti-anxiety medicines like tranylcypromine (Parnate). Patients taking selegiline, a medication to treat early-stage Parkinson's disease and senile dementia, should refrain from taking Calepsin.

Patients should not drink alcoholic beverages while taking this medication to avoid the risk of seizures. They should inform their doctor if they are taking any prescription or over-the-counter medications, including vitamin, mineral or herbal supplements before starting Calepsin treatment.

Calepsin is classified in pregnancy category D by the FDA. Use of this medication can harm an unborn baby. Since it can be passed on through breast milk and harm nursing infants, patients should refrain from breastfeeding while taking Calepsin. Calepsin can decrease the effectiveness of hormone-based birth control pills. Patients will need to talk with their doctor regarding appropriate birth control before beginning this medication. Calepsin may also lower the body's infection-fighting blood cells. Patients on this medication should have their blood and liver functions checked regularly.

Other side effects include drowsiness, dizziness or headaches, vomiting, anxiety, constipation or diarrhea, heartburn, dry mouth, back pain, and impaired motor coordination or unsteadiness of movement. In some rare cases, Calepsin can also cause dysrhythmias, blurred eyesight or double vision, and some loss of blood cells or platelets.

Severe side effects like allergic rashes, breathing difficulties, confusion, depression, suicidal thoughts, chest pain, black or tarry stools, jaundice, and losing touch with reality are very rare, but these are considered serious and need immediate medical attention.

Calepsin is sold under many brand names, and these include Tegretol, Carbatrol, Epitol, Equetro, Finlepsin, Sirtal, Stazepine, Talesmin, Teril, Timonil, Trimonil, and Epimaz. The medication comes in pill form, chewables, extended-release pills and capsules, and a liquid (suspension).

Patients should not stop taking their medication without first consulting their doctor. Suddenly stopping Calepsin can cause an increase in the number of seizures and other unpleasant side effects.

Calepsin has the following structural formula:

Chemical structure of calepsin

• Molecular formula of calepsin is C15H12N2O
• Chemical IUPAC Name is 5H-dibenz[b,f]azepine-5-carboxamide
• Molecular weight is 236.269 g/mol
Calepsin available : 100mg tablets, 100mg/5ml suspension, 200mg tablets

Generic name: Carbamazepine

Brand name(s): Atretol, Biston, Carbamazepen, Carbamezepine, Carbatrol, Carbazepine, Carbelan, Epitol, Equetro, Finlepsin, Karbamazepin, Lexin, Neurotol, Novo-Carbamaz, Nu-Carbamazepine, Sirtal, Stazepin, Stazepine, Taro-Carbamazepine, Tegretal, Tegretol, Telesmin, Teril, Timonil

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