Carbamazepen review

Carbamazepen, also known as CBZ, is an anticonvulsant medication and a mood-stabilizing agent. It acts by decreasing the amount of abnormal excitement in the brain and is used for epilepsy and the treatment of bipolar disorders. Carbamazepen is effective in controlling seizures by blocking certain brain impulses. It is also used for ADD (Attention Deficit Disorder), ADHD (Attention Deficit Hyperactive Disorder), and schizophrenia (a psychiatric condition).

Used by itself or combined with other seizure medications, Carbamazepen is used to calm manic episodes where the patient exhibits extreme mood swings, mixed episodes of mania and depression, and other abnormal moods.

Carbamazepen can be used in the treatment of trigeminal neuralgia, a condition that causes severe pain in the facial nerves. Carbamazepen shifts nerve impulses from the affected facial nerves to ease the pain associated with this condition.

Carbamazepen is also prescribed for mental illnesses including depression, post-traumatic stress disorder, withdrawal from medication and alcohol addictions, restless legs syndrome, diabetes insipidus and a children's disease called chorea.

Patients with a history of bone marrow suppression, porphyria (a blood disorder) and atrioventricular block (a severe heart block problem) should not take Carbamazepen since the medication will make their conditions worse. Patients taking antidepressant medications including amitriptyline (Elavil), desipramine (Norpramin), imipramine (Trofranil), or nortriptyline (Pamelor) should not take Carbamazepen to prevent adverse interactions between the medications.

Other medications with negative interactions include cold and allergy medicines, pain relievers, sleeping pills, muscle relaxants, antidepressants like isocarboxazid (Marplan) and phenelzine (Nardil), and anti-anxiety medicines like tranylcypromine (Parnate). Patients taking selegiline, a medication to treat early-stage Parkinson's disease and senile dementia, should refrain from taking Carbamazepen.

Patients should not drink alcoholic beverages while taking this medication to avoid the risk of seizures. They should inform their doctor if they are taking any prescription or over-the-counter medications, including vitamin, mineral or herbal supplements before starting Carbamazepen treatment.

Carbamazepen is classified in pregnancy category D by the FDA. Use of this medication can harm an unborn baby. Since it can be passed on through breast milk and harm nursing infants, patients should refrain from breastfeeding while taking Carbamazepen. Carbamazepen can decrease the effectiveness of hormone-based birth control pills. Patients will need to talk with their doctor regarding appropriate birth control before beginning this medication. Carbamazepen may also lower the body's infection-fighting blood cells. Patients on this medication should have their blood and liver functions checked regularly.

Other side effects include somnolence, dizziness or headaches, vomiting, anxiety, costiveness or diarrhoea, heartburn, dry mouth, back pain, and impaired motor coordination or unsteadiness of movement. In some rare cases, Carbamazepen has been known to cause cardiac arrhythmias, blurred eyesight or double vision, and some loss of blood cells or platelets.

Severe side effects including allergic rashes, breathing difficulties, confusion, depression, suicidal thoughts, chest pain, black or tarry stools, jaundice, and losing touch with reality are very rare, but are considered serious and need immediate medical attention.

Carbamazepen is sold under many brand names, including Tegretol, Carbatrol, Epitol, Equetro, Finlepsin, Sirtal, Stazepine, Talesmin, Teril, Timonil, Trimonil, and Epimaz. The medication comes in tablet form, chewables, extended-release tablets and capsules, and a liquid (suspension).

Patients should not stop taking their medication without consulting their doctor. Suddenly stopping Carbamazepen may cause an increase in the number of seizures and other unpleasant side effects.

Carbamazepen has the following structural formula:

Chemical structure of carbamazepen

• Molecular formula of carbamazepen is C15H12N2O
• Chemical IUPAC Name is 5H-dibenz[b,f]azepine-5-carboxamide
• Molecular weight is 236.269 g/mol
Carbamazepen available : 100mg tablets, 100mg/5ml suspension, 200mg tablets

Generic name: Carbamazepine

Brand name(s): Atretol, Biston, Calepsin, Carbamezepine, Carbatrol, Carbazepine, Carbelan, Epitol, Equetro, Finlepsin, Karbamazepin, Lexin, Neurotol, Novo-Carbamaz, Nu-Carbamazepine, Sirtal, Stazepin, Stazepine, Taro-Carbamazepine, Tegretal, Tegretol, Telesmin, Teril, Timonil

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