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Carbamezepine

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Carbamezepine

Carbamezepine review





Carbamezepine, also known as CBZ, is an anticonvulsant medication and a mood-stabilizing agent. It acts by decreasing the amount of abnormal excitement in the brain and is used for epilepsy and the treatment of bipolar disorders. Carbamezepine is effective in controlling seizures by blocking certain brain impulses. It is also used for ADD (Attention Deficit Disorder), ADHD (Attention Deficit Hyperactive Disorder), and schizophrenia (a psychiatric condition).

Used by itself or combined with other seizure medicaments, Carbamezepine is used to calm manic episodes where the patient exhibits extreme mood swings, mixed episodes of mania and depression, and other abnormal moods.

Carbamezepine can be used in the treatment of trigeminal neuralgia, a condition that causes severe pain in the facial nerves. Carbamezepine shifts nerve impulses from the affected facial nerves to ease the pain associated with this condition.

Carbamezepine is also prescribed for mental illnesses including depression, post-traumatic stress disorder, withdrawal from medication and alcohol addictions, restless legs syndrome, diabetes insipidus and a children's disease called chorea.

Patients with a history of bone marrow suppression, porphyria (a blood disorder) and atrioventricular block (a severe heart block problem) should not take Carbamezepine since the medication will make their conditions worse. Patients taking antidepressant medicaments including amitriptyline (Elavil), desipramine (Norpramin), imipramine (Trofranil), or nortriptyline (Pamelor) should not take Carbamezepine to prevent adverse interactions between the medicaments.

Other medicaments with known negative interactions include cold and allergy medicines, pain relievers, sleeping pills, muscle relaxants, antidepressants like isocarboxazid (Marplan) and phenelzine (Nardil), and anti-anxiety medicines like tranylcypromine (Parnate). Patients taking selegiline, a medication to treat early-stage Parkinson's disease and senile dementia, should not take Carbamezepine.

Patients should not consume alcoholic beverages while taking this medication to avoid the risk of seizures. Patients should inform their doctor if they are taking any prescription or over-the-counter medicaments, including vitamin, mineral or herbal supplements before starting Carbamezepine treatment.

Carbamezepine is classified in pregnancy category D by the Food and Drug Administration. This means that this medication can harm an unborn baby. As such, patients who are pregnant, plan to become pregnant or become pregnant during treatment should talk with their doctor about the risks involved. Since it can be passed on through breast milk and harm nursing infants, patients should refrain from breastfeeding while taking this medication. Carbamezepine can decrease the effectiveness of hormone-based birth control pills. Patients need to talk with their doctor regarding appropriate birth control before beginning treatment with this medication. Carbamezepine may also lower the body's infection-fighting blood cells. Patients taking this medication should have their blood and liver functions checked regularly.

Other known side effects include drowsiness, dizziness or headaches, emesis, anxiety, constipation or diarrhea, pyrosis, dry mouth, back pain, and impaired motor coordination or unsteadiness of movement. In rare cases, Carbamezepine has been known to cause cardiac arrhythmias, blurred eyesight or double vision, and some loss of blood cells or platelets.

Severe side effects including allergic rashes, breathing difficulties, confusion, depression, suicidal thoughts, chest pain, black or tarry stools, jaundice, and losing touch with reality are very rare, but are considered serious and require immediate medical attention.

Carbamezepine is sold under many brand names, including Tegretol, Carbatrol, Epitol, Equetro, Finlepsin, Sirtal, Stazepine, Talesmin, Teril, Timonil, Trimonil, and Epimaz. The medication comes in tablet form, chewables, extended-release tablets and capsules, and a liquid (suspension).

Patients should not stop taking their medication without consulting their doctor first. Suddenly stopping Carbamezepine may cause an increase in the number of seizures and other unpleasant side effects.

Carbamezepine has the following structural formula:

Chemical structure of carbamezepine


• Molecular formula of carbamezepine is C15H12N2O
• Chemical IUPAC Name is 5H-dibenz[b,f]azepine-5-carboxamide
• Molecular weight is 236.269 g/mol
Carbamezepine available : 100mg tablets, 100mg/5ml suspension, 200mg tablets

Generic name: Carbamazepine

Brand name(s): Atretol, Biston, Calepsin, Carbamazepen, Carbatrol, Carbazepine, Carbelan, Epitol, Equetro, Finlepsin, Karbamazepin, Lexin, Neurotol, Novo-Carbamaz, Nu-Carbamazepine, Sirtal, Stazepin, Stazepine, Taro-Carbamazepine, Tegretal, Tegretol, Telesmin, Teril, Timonil

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