Cardizem is also prescribed as diltiazem, and is commonly used in the treatment of heart rhythm disorders, angina, and hypertension. Cardizem is a calcium channel blocker and which relaxes the muscles of the heart as well as relaxes the blood vessels allowing the heart to pump more steadily and produce better blood flow to meet the needs of the body’s blood demand.
Not all patients should take Cardizem as they may not be able to tolerate it well if there are other health conditions present. Patients with a medical history including low blood pressure, a recent heart attack, or heart conditions such as sick sinus syndrome or AV block without a pacemaker can not take Cardizem. Patients with a medical history which includes congestive heart failure, kidney disease, or liver disease may or may not be able to take Cardizem without incident. Patients with these health conditions will more than likely require special monitoring while undergoing drug therapy with Cardizem.
Cardizem was analyzed and the American Food and Drug Administration rated it a pregnancy risk category C as it was determined that there is a risk that Cardizem will cause harm or birth defects to a developing fetus. Women who are pregnant or are likely to become pregnant should not take Cardizem. This medication has also been proven to pass into the mother’s breast milk and may cause harm to a nursing baby. Women who are nursing should not take Cardizem.
Patients should never take more Cardizem than has been prescribed for them , even in the event of a missed dose. A missed dose can be taken when remembered provided there is ample time before the next scheduled dose. If there is not enough time before the next regularly scheduled dose, the patient should skip the missed dose and return to a regular dosing schedule thereafter. Taking a double dose of this medication or taking doses that are too close together may result in an overdose. An overdose is considered a medical emergency, and should a patient be suspected of taking too much Cardizem they should seek emergency medical care. An overdose may cause chest pain, shortness of breath, fainting, lightheadedness, slow heart rate, and weakness.
Some patients may experience allergic reactions or serious side effects when taking Cardizem. Allergic reactions that present with facial swelling, hives, and difficulty breathing are medical emergencies and proper medical attention is required. Additional serious side effects may include lightheadedness, fainting, slow heart rate, fast heart rate, rapid weight gain, edema, swelling, fever accompanied by a sore throat, headache, and a blistering and peeling rash, shortness of breath, and nausea accompanied by fever, loss of appetite, dark urine, pale stools, weakness, extreme fatigue, stomach pain, or jaundice. These side effects are quite serious and require prompt medical attention.
Most patients do not experience severe side effects and complain only of mild side effects which are likely to include nausea, dizziness, headaches, fatigue, skin rash, stuffy nose, itching, or the sensation of warmth, itching, or tingling underneath the skin. These side effects should be discussed with the prescribing physician as part of follow up care but generally do not require medical treatment.
Medications other than Cardizem may cause interactions and physicians should carefully monitor patient medication changes. Patients should faithfully report any and all medication changes to the prescribing physician, including over the counter medication, prescription drugs, and herbal or vitamin supplements. Patients should never take these additionally without a doctor’s consent. Medications known to interact with Cardizem include HIV medications, beta blockers, seizure medications, antidepressants, antibiotics, St. John’s wort, rifampin, digoxin, cyclosporine, midazolam, lovastatin, dexamethasone, cimetidine, and amiodarone. Patients should also be instructed to avoid grapefruit, grapefruit juice, and other grapefruit products as these can cause an interaction with Cardizem.
Cardizem has the following structural formula:
• Molecular formula of cardizem is C22H26N2O4S
• Chemical IUPAC Name is [2-(2-dimethylaminoethyl)-5-(4-methoxyphenyl)-3-oxo-6-thia-2- azabicyclo[5.4.0]undeca-7,9,11-trien-4-yl]ethanoate
• Molecular weight is 414.519 g/mol
• Cardizem available : 30mg tablets, 60mg tablets, 90mg tablets
Generic name: Diltiazem
Brand name(s): Acalix, Adizem, Altiazem, Anginyl, Angizem, Anoheal, Apo-Diltiaz, Britiazim, Bruzem, Calcicard, Citizem, Cormax, Deltazen, Dilacor, Diladel, Dilcontin, Dilpral, Dilrene, Dilt-cd, Diltahexal, Diltia, Diltiazem HCL, Dilticard, Dilzem, Dilzen, Endrydil, Herbesser, Masdil, Novo-Diltazem, Nu-Diltiaz, Syn-Diltiazem, Tiazac Tildiem
Review published on: 15 June 2007
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