belongs to a group of medications called beta-blockers, which affect the heart
flow within the veins
. Carvedilolum is a non-selective beta-blocker, which means that it blocks both beta 1 (responsible for heart rate and heartbeat strength) and beta 2 (responsible for smooth muscle
Carvedilolum is a generic medication distributed under the brand names Dilatrend, Eucardic, Coreg
and Coreg CR. It is used for the treatment of mild to moderate congestive heart failure
(CHD). It is also indicated for hypertension
, or high blood pressure
, and as treatment and prevention of heart attacks.
Carvedilolum works by slowing the heart's rhythm and lowering the heart's pumping force. It also relaxes the blood vessels
enabling the blood to travel through the veins and arteries without difficulty. In doing so, blood pressure is lowered and the risk for heart failure is reduced.
Patients should inform their doctor if they have a history of allergies
to this medication, suffer from asthma
, slow or irregular heartbeat
, or liver
disease, all of which may worsen with Carvedilolum use. Patients should also tell their doctor if they have diabetes
, low blood sugar, low blood pressure, hyperthyroidism
(an excess of thyroid hormones), Prinzmetal's angina (unexplained chest pain), or pheochromocytoma (tumors in glands near the kidneys).
The doctor should also be apprised of any prescription or over-the-counter medications, including vitamin, mineral and herbal supplements that the patient may be taking, as they may cause adverse effects when taken with Carvedilolum. Other counterindications include surgery, consuming alcoholic beverages or taking any medications containing alcohol, and driving a car or operating heavy machinery within two hours after taking the medication.
Women who are pregnant, plan to become pregnant or become pregnant while taking Carvedilolum must inform their doctor immediately. This medication has been classified by the Food and Drug Administration under pregnancy category C, which means that it is harmful to an unborn fetus. It can also harm nursing infants. Patients who are nursing an infant should refrain from taking Carvedilolum without notifying their doctor.
Patients taking Carvedilolum may experience episodes of dizziness
, lightheadness, and even fainting. Another side effect is hyperglycemia, or high blood sugar. Excessive thirst, frequent urination
, extreme hunger, weakness and blurred vision are symptoms of hyperglycemia. If patients taking Carvedilolum exhibit any of these symptoms, they should call their doctor as soon as possible.
Other side effects include weakness and languidness, cephalalgias, nausea
, joint pain
, coughing, dry eyes, changes in vision, and numbness or tingling of the arms or legs
. Side effects like fainting, breathing and swallowing
difficulties, weight gain, chest pain
of the arms and legs, rashes, hives
, and slow or irregular heartbeat are considered serious and require immediate medical attention.
Carvedilolum comes in white, oval, film-coated tablets of different milligram dosages, and extended release capsules. In tablet form, the prescribed dose is two times a day to be taken with food. Carvedilolum in extended release capsules is taken once a day with food, usually in the mornings. The medication should be taken whole, not crushed, chewed or ground, at the same time each day with a full glass of water.
Carvedilolum can control symptoms, but cannot eliminate the condition altogether. This medication is merely one of the elements in a comprehensive treatment program that may include a special diet, exercise and proper weight control. Patients are advised to take Carvedilolum regularly, sometimes for the rest of their lives. Suddenly going off the medication without prior medical advice can cause severe chest pain, irregular heartbeat, and even a heart attack
Carvedilolum has the following structural formula:
• Molecular formula of carvedilolum is C24H26N2O4
• Chemical IUPAC Name is 1-(9H-carbazol-4-yloxy)-3-[2-(2-methoxyphenoxy)ethylamino]propan-2-ol
• Molecular weight is 406.474 g/mol
• Carvedilolum available : 3.125mg tablets, 6.25mg tablets, 12.5mg tablets, 25mg tablets