Catapresan is a brand name for the generic medication clonidine hydrochloride. It is given for the treatment of hypertension, or high blood pressure. Hypertension is when too much blood is being pumped through arteries that are too narrow or blocked. Its symptoms can include headaches, dizzy spells, or nosebleeds, though it often has no symptoms at all. Even without symptoms, it can be threatening to your health and should be treated with a medication such as Catapresan. Catapresan comes in tablets and can be given by itself or along with other antihypertensive medications. Catapresan is given at an initial low dose of 0.1 mg, and is increased daily until the optimal dosage is reached. It works quickly, producing a measurable decrease in blood pressure within thirty to sixty minutes.
Most side effects of Catapresan are mild and decrease in severity the longer you take it. The most frequent are dry mouth, which occurs in about 40% of patients, drowsiness in about 33%, dizziness in about 16%, constipation about 10%, and sedation about 10%. There are other possible side effects to Catapresan, but they are very rare. They can include weakness, fatigue, headache, withdrawal symptoms, pallor, lower tolerance to alcohol, and fever. Other rare side effects include congestive heart failure, increased or slowed heart rate, palpitations, abnormal readings of your ECG, depression, insomnia, vivid dreams, restlessness and anxiety, delirium or hallucinations, rash or hives, itchy skin, swelling, hair loss, nausea or vomiting, loss of appetite or weight gain, malaise, loss of libido, frequent night time urination, and abnormalities in the function of the liver.
If you are taking Catapresan, it is important to be aware that it can increase the depressive effects of alcohol, barbiturates, or other sedative drugs. If you are taking another medication that affects the heart’s sinus node function, you should be especially careful in taking Catapresan, since these second medications may reduce Catapresan’s ability to lower blood pressure. In addition, taking Catapresan with Amitriptyline has been shown to increase the production of corneal lesions.
It is important not to stop taking Catapresan without talking to your doctor first; you could experience severe withdrawal symptoms unless you are gradually weaned from the medication. These withdrawal symptoms could include rapid rise in blood pressure and levels of catecholamine in the plasma. You should also use extreme caution if you have recently had a heart attack, if you have chronic kidney failure, coronary insufficiency, or disease of the blood vessels in the brain.
Catapresan is in Pregnancy Category C, which means that it is not known whether it is safe to use during pregnancy, or whether it will harm a developing fetus. However, it is known that Catapresan passes into breast milk, so you should use caution in taking Catapresan if you are nursing or planning to nurse a child. It has not been determined whether Catapresan is safe for children under twelve, so it is not recommended for pediatric use in young children.
Catapresan has the following structural formula:
• Molecular formula of catapresan is C9H9Cl2N3
• Chemical IUPAC Name is N-(2,6-dichlorophenyl)-4,5-dihydro-1H-imidazol-2-amine
• Molecular weight is 230.093 g/mol
• Catapresan available : 0.1mg tablets, 0.2mg tablets, 0.3mg tablets
Generic name: Clonidine
Brand name(s): Adesipress, Catapres, Catapressan, Catarpres, Catarpresan, Chlornidinum, Clonidin, Clonidinum, Clonistada, Combipres, Dixarit, Duraclon, Duraclont, Ipotensium, Isoglaucon
Review published on: 23 March 2008
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