Cephaclor review

Cephaclor is a second-generation broad-spectrum antibiotic from the antibacterial medicaments known as cephalosporins. It is available by the brand names Ceclor, Ceclor CD, Ceclor Pulvules, and Raniclor.

Cephaclor is used to treat bacterial infections like pneumonia, and infections of the ear, lung, skin, throat, and urinary tract. It works by penetrating the body's tissues and fluids, and obstructing the growth of the bacteria causing the infection.

Patients should avoid Cephaclor if they are allergic to cephalosporin, penicillin or other antibiotics. If they have a kidney disorder or any digestive disease like colitis, patients should inform their doctor of these diseasees and get a prescription for a different dose and be monitored during the course of treatment.

In the suspension liquid, Cephaclor contains sucrose, which is not advisable for diabetics. Pregnant women or those planning to become pregnant should talk with their doctor before treatment. Since Cephaclor can be passed on through breast milk, nursing mothers need to tell their doctor if they are breastfeeding before taking any of the medicament, so as not to affect nursing infants.

Patients should not take antacids that contain magnesium or aluminum while undergoing Cephaclor treatment as these can lower the efficacy of the antibiotic. Some of these antacids are Rolaids, Maalox, Mylanta, and Milk of Magnesia. Other medicaments known to affect Cephaclor include Warfarin (an anticoagulant), Probenecid (an arthritis and gout medicament), loop diuretics or water pills, and other antibiotics. Patients should inform their doctor of any other medicaments, vitamins or herbal supplements they are taking prior to starting their Cephaclor treatment.

Some known side effects include allergic reactions in the form of rashes, itching, uticaria (hives), fever, serum sickness-like reactions (hypersensitivity), arthralgia (joint pain), and anaphylaxis (whole body atopy). Patients may experience diarrhea, nausea, emesis, stomach upset, transient hepatitis, jaundice, headaches and Stevens-Johnson syndrome (a deadly allergic skin disease). In rare cases, blood disorders, nephritis (kidney inflammation), hyperactivity, nervousness, disrupted sleep, hallucinations, confusion and dizziness may occur.

Patients should stop taking Cephaclor and seek emergency medical attention if they experience severe allergic reactions which include breathing difficulties, skin edema of the facial tissue, rashes, redness or itching, nausea, emesis or diarrhea, blood or mucus in their stools, or unexplained bleeding and bruising. All side effects should be reported to your doctor, particularly if they interfere with day-to-day activities.

Cephaclor is available in purple and white 250 mg. capsules, purple and gray 500 mg. capsules, and as a suspension (liquid) in strawberry flavor. Ceclor CD is manufactured in blue tables of 375 and 500 mgs. When taking Cephaclor in liquid form, the bottle needs to be shaken and the correct dose accurately measured using a measuring spoon or cup.

Cephaclor should be taken with a full glass of water on a full or empty stomach. Ceclor CD, in extended release capsules, should be taken with food or milk to prevent stomach upset. Ceclor CD tablets are created to be released slowly in the body, so it is advisable not to cut, grind or chew them.

While symptoms of an infection usually disappear quickly, the bacteria causing the infection may still remain in the body. Cutting the medicament process short may cause the body to develop a resistance to the antibiotics.

Cephaclor needs to be taken regularly for the prescribed period to make sure the body maintains a consistent level of the medicament, and to obtain the best results from it. Any unused medicament needs to be disposed of after 14 days.

Cephaclor has the following structural formula:

Chemical structure of cephaclor

• Molecular formula of cephaclor is C15H14ClN3O4S
• Chemical IUPAC Name is (6R,7R)-7-[(2-amino-2-phenylacetyl)amino]-3-chloro-8-oxo- 5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• Molecular weight is 367.8074 g/mol
Cephaclor available : 250mg capsules, 500mg capsules, 187mg/5ml suspension 100ml bottle, 375mg/5ml suspension 100ml bottle, 125mg/5ml suspension 150ml bottle, 250mg/5ml suspension 150ml bottle, 187mg/5ml suspension 50ml bottle, 375mg/5ml suspension 50ml bottle, 125mg/5ml suspension 75ml bottle, 250mg/5ml suspension 75ml bottle

Generic name: Cefaclor

Brand name(s): Alenfral, Alfacet, Alfatil, Ceclor, Ceclor CD, Cefaclorum, Distaclor, Kefral, Panacef, Panoral, Raniclor

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