Medicalook
Medicalook

Chlorbutin

http://www.medicalook.com
Chlorbutin

Chlorbutin review





Chlorbutin is a powerful chemotherapy medication used in treating chronic lymphocytic leukemia. Chlorbutin was used against some types of non-Hodgkin lymphoma and ovarian carcinoma and as an immunosuppressive medication for inflammatory and autoimmune conditions, including nephrotic syndrome. Now, it is mainly used in cases of chronic lymphocytic leukemia.

Chlorbutin is distributed by GlaxoSmithKline under the brand name Leukeran. It is for patients with Hodgkin's disease, chronic lymphocytic leukemia, and Waldenstrom's macroglobulinaemia, among others.

There is a varying dosage for each condition. For example, for Waldenstrom's macroglobulinaemia, the initial dose is 6-12 mg per day until leucopenia develops. After, the maintenance dose is 2-8 mg per day. Since Chlorbutin comes in a 2 mg brown tablet, the maintenance can range from one to four tablets per day.

Chlorbutin should be taken with proper supervision of a physician. It is also best taken on an empty stomach with lots of water. Make sure that you do not chew or crush the tablet.

If you miss a dosage, do not take a double dose at your next scheduled dosage. Inform your physician of the missed dose and continue with your usual dosage. If you vomit right after taking Chlorbutin, seek your physician's advice whether to take another or not.

If you are taking this medication, bruising or bleeding is normal. Since the blood will lose platelet production, the ability of the blood to clot is affected. Contact your physician if you experience bleeding gums or blood spots.

Another side effect is anemia. When you have anemia, you feel tired often. You also feel as if you are breathless. At the same time, wamble and emesis may be experienced. These side effects can be controlled or lessened by some anti-emetic medications.

Some patients will experience a lowered resistance level. Due to this, they may be prone to illnesses like colds. While taking Chlorbutin, you may lose your appetite. There are still some tips that your physician or dietician can give you so you can maintain a healthy weight.

In rare cases, some people taking Chlorbutin develop mouth sores, ulcers, diarrhea, seizures, or fits, while some also report changes in food taste. There may also be effects on the liver that are reversible after treatment.

There are some fertility issues when taking Chlorbutin. That is why it is advised to discuss contraception with your physician before taking this medication.

Patients taking azidamfenicol are cautioned against taking Chlorbutin. A combination of these medications may result in additive toxicity, which can be fatal or cause permanent damage.

There might be medications prescribed alongside Chlorbutin to prevent or lessen the possible side effects. These include anti-emetic medications and anti-diarrhea medications. Keep in mind that you should inform your physician right away of any reaction of the medications. Physicians may change your prescribed medications based on your response to the treatment.

Chlorbutin is mutagenic, meaning that it can cause mutations in a person's Deoxyribonucleic acid. Pregnant women should be aware that there are reports that fetus may be affected by Chlorbutin. To be safe, pregnant women are advised to talk with their physician regarding whether to breastfeed or not.

Chlorbutin has the following structural formula:

Chemical structure of chlorbutin


• Molecular formula of chlorbutin is C14H19Cl2NO2
• Chemical IUPAC Name is 4-[4-[bis(2-chloroethyl)amino]phenyl]butanoic acid
• Molecular weight is 304.212 g/mol
Chlorbutin available : 2mg tablets

Generic name: Chlorambucil

Brand name(s): Ambochlorin, Amboclorin, Chlocambucil, Chloraminophen, Chloraminophene, Chlorbutine, Chloroambucil, Chlorobutin, Chlorobutine, Ecloril, Elcoril, Leukeran, Leukersan, Leukoran, Linfolizin, Linfolysin, Pepstatin

  Your Chlorbutin review