Chloromycetin review

Chloromycetin can also be prescribed as Pentamycetin or chloraphenical and is used in the treatment of bacterial infection, with the ophthalmic solution used exclusively for infections of the eye. Chloromycetin should not be used with other antibiotics.

Chlormycetin is often used for bacterial infections which have not been successfully treated with other antibiotics. Patients should take the entire prescription of the medication in order to be assured that the infection has cleared, even after symptoms are alleviated.

Chloromycetin is not appropriate for all patients and it should not be dispensed without a thorough medical examination and medical history. Patients with a history of liver disease or kidney disease may not be able to tolerate Chloromycetin without dosage adjustments, if at all. Patients suffering from severe infections which require an antibiotic as strong as Chloromycetin may not be able to clearly communicate with the physician in order to determine whether or not this medication is appropriate for them. Patients with severe conditions should wear medical alert bracelets to facilitate necessary information. Chloromycetin is dispensed via intravenous medications.

The American Food and Drug Administration rated Chloromycetin as a pregnancy risk category C, which means that this medication is not recommended for women who are pregnant as there is a risk of causing harm or birth defects to a developing fetus. This medication also passes through the mother’s breast milk and should not be prescribed to women who are nursing.

It is not uncommon for patients taking Chloromycetin to experience side effects, however, some side effects indicate a serious health risk. Allergic reactions (swelling of the lips, mouth, tongue, or throat, hives, and difficulty breathing) as well as bone marrow depression, aplastic or hypoplastic anemia, fevers, rashes, and the inability to urinate indicate other health effects.

Most patients are likely to experience side effects such as upset stomach, nausea, vomiting, headaches, confusion, mental cloudiness, and mild depression. If patients develop dementia, severe depression, or other serious mental health issues, the medication should be discontinued immediately.

Blood tests will be required for the first two days to monitor the platelet count in patients undergoing drug therapy with Chloromycetin. Liver function and kidney function tests may possibly be necessary at the physician’s discretion.

Children need to be monitored for Gray syndrome, which will present as refusal to nurse or feed from a bottle, loss of interest in food, loose green stools, gray skin tone, flaccidity, lowered body temperature, and refractory lactic acidosis. Unfortunately, few children survive Gray’s syndrome and death may occur within a few hours of the onset of the disease.

Overdosing by the patient is nearly impossible, as Chloromycetin is administered via IV delivery, however an overdose can still happen. The symptoms of an overdose are likely to include nausea, vomiting, mouth odor or unpleasant taste in the mouth, bone marrow suppression, and diarrhea.

Complications can set in months after the conclusion of therapy with Chloromycetin. Patients should be urged to schedule and keep follow up appointments even if they are asymptomatic. Complications can be severe and can include the immune system, kidneys, and liver. If patients develop a fever, sore throat, vomiting, diarrhea, bruising, bleeding, jaundice, numbness, weakness in hands or feet, or itching. Parents should watch for infants developing post treatment symptoms such as drowsiness, abdominal distention, a blue or gray skin tone, a refusal to feed, and problems breathing as these can be the early signs of Gray’s syndrome. Immediate medical attention is needed for children or adults if any of these symptoms occur.

Chloromycetin has the following structural formula:

Chemical structure of chloromycetin

• Molecular formula of chloromycetin is C11H12Cl2N2O5
• Chemical IUPAC Name is 2,2-dichloro-N-[1,3-dihydroxy-1-(4-nitrophenyl)-propan-2-yl]-acetamide
• Molecular weight is 323.129 g/mol

Generic name: Chloramphenicol

Brand name(s): Alficetyn, Ambofen, Amphenicol, Amphicol, Amseclor, Anacetin, Aquamycetin, Austracil, Austracol, Biocetin, Biophenicol, Catilan, Chemicetin, Chemicetina, Chlomin, Chlomycol, Chlora-Tabs, Chloramex, Chloramfenikol, Chloramficin, Chloramfilin, Chloramphenicole, Chloramsaar, Chlorasol, Chloricol, Chlornitromycin, Chlorocaps, Chlorocid, Chlorocide, Chlorocol, Chlorofair, Chloromax, Chloromycetny, Chloromyxin, Chloronitrin, Chloroptic, Chlorovules, Cidocetine, Ciplamycetin, Cloramfen, Cloramficin, Cloramicol, Cloramidina, Cloroamfenicolo, Clorocyn, Cloromisan, Clorosintex, Comycetin, Cylphenicol, Desphen, Detreomycin, Detreomycine, Dextromycetin, Doctamicina, Econochlor, Embacetin, Emetren, Enicol, Enteromycetin, Erbaplast, Ertilen, Farmicetina, Farmitcetina, Fenicol, Globenicol, Glorous, Halomycetin, Hortfenicol, Intramycetin, Isicetin, Ismicetina, Isophenicol, Juvamycetin, Kamaver, Kemicetina, Kemicetine, Klorita, Leukamycin, Leukomyan, Leukomycin, Levomicetina, Levomitsetin, Levomycetin, Liquichlor, Loromisan, Loromisin, Mastiphen, Mediamycetine, Medichol, Micloretin, Micochlorine, Micoclorina, Microcetina, Mychel, Mycinol, Normimycin V, Novochlorocap, Novomycetin, Novophenicol, Oftalent, Oleomycetin, Opclor, Opelor, Ophthochlor, Ophthoclor, Ophthocort, Ophtochlor, Optomycin, Otachron, Otophen, Owadziak, Pantovernil, Paraxin, Pedraczak, Pentamycetin, Pflanzol, Quellada, Quemicetina, Rivomycin, Romphenil, Ronphenil, Septicol, Sificetina, Sintomicetina, Sno-Phenicol, Stanomycetin, Synthomycetin, Synthomycetine, Synthomycine, Tevcocin, Tevcosin, Tifomycin, Tifomycine, Tiromycetin, Treomicetina, Tyfomycine, Unimycetin, Veticol, Viceton

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