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Chlorpropamide

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Chlorpropamide

Chlorpropamide review





Chlorpropamide is a drug that helps to control high blood sugar and prevent the risk of kidney problems, heart disease, blindness, impotency and stroke. It stimulates the release of natural insulin of the body, which lowers the level of blood sugar.

Chlorpropamide is a prescribed drug distributed under the brand names Orinase, Diabinese, and Tolinase. Chlorpropamide is sold under several generic names such as Acetohexamide, Tolbutamide and Tolazamide. It is a drug used by individuals who have type II diabetes.

Chlorpropamide is taken orally usually once a day after breakfast or as prescribed by the doctor. The dosage may vary depending on the medical condition and the response of the patient to the therapy sessions. It is best to take the medicine at the same time regularly in order to get its full benefit. Avoid using it more than what is prescribed to avoid overdose.

Patients using Chlorpropamide for medication may experience side effects such as diarrhea, weight gain, nausea, vomiting and loss of appetite. These are only minor side effects but it is still important to inform your doctor about these.

There are also rare cases of serious side effects that include unusual fatigue, irregular heartbeat, mood changes, weakness of the muscles, dark color stool, swelling of feet or hands, muscle weakness, vomiting, yellowish skin and eyes and stomach pains. The patient should be brought to a hospital if any of the serious side effects occur.

Taking Chlorpropamide can cause hypoglycemia or low blood sugar. This side effect may be experienced by patients who do not have enough intakes of calories. It is advisable to always bring some glucose tablets to raise the blood sugar if necessary. You may also use substitutes such as orange juice, candy, honey and sugar.

It is essential to closely monitor your blood sugar if you are using Chlorpropamide for medication.

If you need to use Chlorpropamide as medication, you must inform your doctor if you have any allergies with the drug or with similar drug. You must also tell your doctor if you have other medical condition such as kidney problems, heart problems, thyroid problems, liver problem, poor diet and mineral imbalance.

The drug affects your vision and can cause drowsiness so it is advised not to engage in activities that requires normal alertness such as operating machines, driving and other extreme activities.

Patients who are under medication should avoid alcoholic drinks because it increases the risk of having hypoglycemia. Alcohol also interacts with the drug that can cause discomfort and unwanted effects such as stomach pain, nausea, facial flushing and dizziness.

While under medication with Chlorpropamide, it is best to avoid too much exposure to sunlight because the drug causes the body to be more sensitive with the sun. Wear some protective clothing when going outdoors.

Pregnant women and breastfeeding mothers should consult first the doctor before taking the medicine to avoid any risk to the infant.

This drug is only prescribed by doctors and should not be shared to anyone.

Chlorpropamide has the following structural formula:

Chemical structure of chlorpropamide


• Molecular formula of chlorpropamide is C10H13ClN2O3S
• Chemical IUPAC Name is N-(4-chlorophenyl)sulfonylmethanamide
• Molecular weight is 276.741 g/mol
Chlorpropamide available : 100mg tablets and 250mg tablets

Brand name(s): Adiaben, Apo-Chlorpropamide, Asucrol, Catanil, Chlorodiabina, Chloronase, Chloropropamide, Chlorpropamid, Clorpropamide, Diabaril, Diabechlor, Diabenal, Diabenese, Diabeneza, Diabet-Pages, Diabetoral, Diabinese, Diamel Ex, Dynalase, Glisema, Glucamide, Hexathane, Insulase, Meldian, Melitase, Mellinese, Millinese, Novo-Propamide, Oradian, Stabinol

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