Chlorthalidone review

Chlorthalidone is a prescribed thiazide diuretic, more commonly known as a water pill, that is used to cure fluid retention (edema) caused by the bodys absorption of salt. It transfers excess water and salt into the urine through the kidneys. It used in the treatment or control of hypertension, heart disease, kidney disorders, or side effects from taking steroids or estrogen. Its more popular brand names include Clorpres, Thaliton, and Hygroton.

It is essential that people who are unable to urinate to not take this drug; otherwise, there may be severe side effects. It is also important to inform your doctor if you have asthma, kidney or liver disease, diabetes, renal dysfunction, lupus, or allergies to sulfa drugs. Failure to do so may result in severe allergic reactions, sensitivity reactions, or in worst case scenarios, hepatic comas.

Studies have shown no adverse effects on unborn babies; however, breastfeeding women should tell their doctors first before taking Clorthalidone.

An orally ingested drug, Chlorthalidone is usually taken one or two times a day. If your physician prescribes otherwise, however, you should follow what he or she gives you strictly. It should not be taken on an empty stomach, which may result in acute discomfort. If a dosage is missed, take it as soon as you remember, but do not take more than the prescribed amount at one time to compensate. In case of accidental overdosage, immediately seek medical attention. Symptoms include vomiting, nausea, muscle pain, and excessive weakness.

Sleep-inducing medicines, such as muscle relaxants, cough medicine, and sleeping pills should be avoided while taking Chlorthalidone, as these may exacerbate some of the side effects. If these drugs must be taken, inform your doctor in advance to take extra precautions. When taking Chlorthalidone, make sure to avoid drinking alcohol as well – it can also worsen the potential side effects of the drug. Chlorthalidone also makes skin more sensitive to UV rays, so avoid being under the sun too much or using any tanning beds. Chlorthalidone makes the body get rid of water more quickly, so be certain to stay well-hydrated all through out the day.

While doctors often prescribe special diets to patients taking the drug, these are generally low in salt and sodium and high in potassium, all of which compensate for the body’s rapid water disposal.

The primary – and certainly the most expected – side effect of taking Chlorthalidone is a significant increase in urination, although after a few weeks, this should also subside. Dizziness, muscle cramps, nausea, an upset stomach, vomiting, hair loss, weakness, and hair loss are all potential side effects, but these are often very minimal. To be safe, however, immediately inform your physician if they become quite severe. In case of numbness, bruising, excessive bleeding, difficulty breathing, or fevers, however, approach your doctor right away and have yourself checked.

Have regular blood and urine tests with your physician to make sure there are no adverse long-term effects. It must be stored at room temperature at a dry location. Once past the expiry date, get rid of it immediately.

Chlorthalidone has the following structural formula:

Chemical structure of chlorthalidone

• Molecular formula of chlorthalidone is C14H11ClN2O4S
• Chemical IUPAC Name is 2-chloro-5-(1-hydroxy-3-oxo-1,2-dihydroisoindol-1-yl)-benzenesulfonamide
• Molecular weight is 338.767 g/mol
Chlorthalidone available : 25mg tablets, 50mg tablets, 100mg tablets

Brand name(s): Chlorothalidone, Chlorphthalidolone, Chlorphthalidone, Chlorthalidon, Clodronic Acid, Higroton, Hygroton, Igroton, Isoren, Natriuran, Oradil, Phthalamodine, Phthalamudine, Renon, Saluretin, Tenoretic, Thalitone, Zambesil

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